Uveal melanoma (UM), a rare cancer of the eye, is distinct from cutaneous melanoma by its
etiology, the mutation frequency and profile, and its clinical behavior including resistance to …

Uveal melanoma (UM) is the most common primary intraocular malignancy affecting adults.
Despite successful local treatment of the primary tumour, metastatic disease develops in up …

Uveal melanoma is the most common type of intraocular cancer with a low mean annual
incidence of 5-10 cases per million. Tumours are located in the choroid (90%), ciliary body …

Uveal melanoma, which is the most common primary intraocular malignancy in adults,
arises from melanocytes within the iris, ciliary body and choroid. The diagnosis is based …

Liquid biopsy is a common term referring to circulating tumor cells and other biomarkers,
such as circulating tumor DNA (ctDNA) or extracellular vesicles. Liquid biopsy presents a …

Purpose: To develop a molecular tool to detect circulating tumor–derived DNA (ctDNA) in
the plasma from patients with uveal melanoma as a marker of tumor burden and monitor …

Uveal melanoma (UM) is the second most frequent type of melanoma. Therapeutic options
for UM favor minimally invasive techniques such as irradiation for vision preservation. As a …

Circulating tumour cells (CTCs) are cells of solid tumour origin detectable in the peripheral
blood. Their occurrence is considered a prerequisite step for establishing distant …

Current technologies to identify and characterize circulating tumor cells (CTCs) and
circulating tumor microemboli (CTMs) among hundreds of millions of leukocytes in the …

Simple Summary To date, there is no treatment for metastatic uveal melanoma. Identifying its
metastatic spread is essential. Liquid biopsy can identify patients at risk of metastatic spread …