Vaccines for leishmaniasis in the fore coming 25 years

CB Palatnik-de-Sousa - Vaccine, 2008 - Elsevier
Human vaccination against leishmaniasis using live Leishmania was used in Middle East
and Russia (1941–1980). First-generation vaccines, composed by killed parasites induce …

Vaccine candidates for leishmaniasis: a review

R Nagill, S Kaur - International immunopharmacology, 2011 - Elsevier
Leishmaniasis is a diverse group of clinical syndromes caused by protozoan parasites of the
genus Leishmania. The clinical manifestation of the disease varies from self-limiting …

[PDF][PDF] Impact of canine control on the epidemiology of canine and human visceral leishmaniasis in Brazil.

CB Palatnik-de-Sousa, WR dos Santos… - The American journal …, 2001 - academia.edu
Brazil is the only country endemic for zoonotic visceral leishmaniasis (ZVL) that regularly
conducts epidemiologic and prophylactic control programs that involve the treatment of …

Long lasting protection against canine kala-azar using the FML-QuilA saponin vaccine in an endemic area of Brazil (Sao Goncalo do Amarante, RN)

GP Borja-Cabrera, NNC Pontes, VO Da Silva… - Vaccine, 2002 - Elsevier
Naturally exposed dogs of an endemic area were vaccinated with the fucose mannose
ligand (FML) antigen of Leishmania donovani in formulation with QuilA saponin. The 100 …

A phase III trial of efficacy of the FML-vaccine against canine kala-azar in an endemic area of Brazil (Sao Goncalo do Amaranto, RN)

VO da Silva, GP Borja-Cabrera, NNC Pontes… - Vaccine, 2000 - Elsevier
Protection against canine kala-azar was investigated in naturally exposed dogs of an
endemic area, vaccinated with the fucose mannose ligand (FML)-vaccine of Leishmania …

[HTML][HTML] Reflexões sobre a qualidade do diagnóstico da leishmaniose visceral canina em inquéritos epidemiológicos: o caso da epidemia de Belo Horizonte, Minas …

WA Alves, PD Bevilacqua - Cadernos de Saúde Pública, 2004 - SciELO Brasil
No Brasil, a leishmaniose visceral (LV) apresenta quadros graves de endemias e epidemias
havendo, nos últimos anos, uma propagação da doença por vários estados que antes não …

Vaccines for canine leishmaniasis

CB Palatnik-de-Sousa - Frontiers in immunology, 2012 - frontiersin.org
Leishmaniasis is the third most important vector-borne disease worldwide. Visceral
leishmaniasis (VL) is a severe and frequently lethal protozoan disease of increasing …

Diagnosis of American visceral leishmaniasis in humans and dogs using the recombinant Leishmania donovani A2 antigen

FAA Carvalho, H Charest, CAP Tavares… - … and infectious disease, 2002 - Elsevier
A2 proteins are expressed in the amastigote stage of Leishmania donovani and are
composed predominantely by a conserved repetitive element. Here, we have investigated …

Comparison of two commercial vaccines against visceral leishmaniasis in dogs from endemic areas: IgG, and subclasses, parasitism, and parasite transmission by …

CB Fernandes, JTM Junior, C de Jesus… - Vaccine, 2014 - Elsevier
Background The incidence of zoonotic canine visceral leishmaniasis (CVL) would decrease
if dogs were effectively vaccinated; however, additional data on the efficacy of canine …

[HTML][HTML] Decrease of the incidence of human and canine visceral leishmaniasis after dog vaccination with Leishmune® in Brazilian endemic areas

CB Palatnik-de-Sousa, I Silva-Antunes… - Vaccine, 2009 - Elsevier
Leishmune®, the first prophylactic vaccine licensed against canine visceral leishmaniasis
(CVL), has been used in Brazil since 2004, where seropositive dogs are sacrificed in order …