Abstract Background/Aims: On behalf of the Drug and Therapeutics, and Ethics Committees
of the Pediatric Endocrine Society, we sought to update the guidelines published in 2003 on …

The important role of GH in the control of mammalian longevity was first deduced from
extended longevity of mice with genetic GH deficiency (GHD) or GH resistance. Mice with …

Genome editing is a powerful new tool for making precise alterations to an organism's
genetic material. Recent scientific advances have made genome editing more efficient …

Introduction. Human neurodegenerative diseases increase progressively with age and
present a high social and economic burden. Growth hormone (GH) and insulin-like growth …

A primary objective of the Childhood Cancer Survivor Study (CCSS) is to characterize the
major chronic health conditions faced by childhood cancer survivors, and to determine the …

Postnatal growth and development of the human body and its specific organs are regulated
by a complex network of local and systemic factors which is poorly understood. This review …

THOMAS A. WILSON, MD, SUSAN R. ROSE, MD, PINCHAS COHEN, MD, ALAN D. ROGOL,
MD, PHD, PHILIPPE BACKELJAUW, MD, ROSALIND BROWN, MD, DANA S. HARDIN, MD …

Context: Treatment with GH has been used to correct the growth deficit in children with GH
deficiency (GHD). Although successful in increasing height velocity, such treatment often …

The growth hormone (GH)–insulin-like growth factor (IGF) cascade is central to the
regulation of growth and metabolism. This article focuses on the history of the components of …

Introduction: Growth hormone (GH) therapy is used to treat a variety of growth disorders in
childhood/adolescence. Its efficacy is thought to be dependent on patients' adherence to …