Neuropathology of substance use disorders

JL Cadet, V Bisagno, CM Milroy - Acta neuropathologica, 2014 - Springer
Addictions to licit and illicit drugs are chronic relapsing brain disorders that affect circuits that
regulate reward, motivation, memory, and decision-making. Drug-induced pathological …

3, 4-methylenedioxymethamphetamine (MDMA): current perspectives

JS Meyer - Substance abuse and rehabilitation, 2013 - Taylor & Francis
Ecstasy is a widely used recreational drug that usually consists primarily of 3, 4-
methylenedioxymethamphetamine (MDMA). Most ecstasy users consume other substances …

MDMA: interactions with other psychoactive drugs

WMY Mohamed, SB Hamida, JC Cassel… - Pharmacology …, 2011 - Elsevier
3, 4-Methylenedioxymethamphetamine (MDMA, ecstasy) is one of the most widely abused
illegal drugs. Some users self-report euphoria and an increased perception and feeling of …

Evidence for chronically altered serotonin function in the cerebral cortex of female 3, 4-methylenedioxymethamphetamine polydrug users

CR Di Iorio, TJ Watkins, MS Dietrich… - Archives of general …, 2012 - jamanetwork.com
Context MDMA (3, 4-methylenedioxymethamphetamine, also popularly known as “ecstasy”)
is a popular recreational drug that produces loss of serotonin axons in animal models …

Imaging biomarkers of the neuroimmune system among substance use disorders: a systematic review

EA Woodcock, AT Hillmer, GF Mason… - Complex Psychiatry, 2019 - karger.com
There is tremendous interest in the role of the neuroimmune system and inflammatory
processes in substance use disorders (SUDs). Imaging biomarkers of the neuroimmune …

MDMA toxicity and pathological consequences: a review about experimental data and autopsy findings

E Turillazzi, I Riezzo, M Neri, S Bello… - Current …, 2010 - ingentaconnect.com
Studies conducted in humans or in animals explored the presence, nature and potential
causes of 3, 4-methylenedioxymethamphetamine (MDMA) toxicity. According to literature …

MDMA administration decreases serotonin but not N-acetylaspartate in the rat brain

SA Perrine, F Ghoddoussi, MS Michaels, EM Hyde… - Neurotoxicology, 2010 - Elsevier
In animals, repeated administration of 3, 4-methylenedioxymethamphetamine (MDMA)
reduces markers of serotonergic activity and studies show similar serotonergic deficits in …

Increases in retinal nerve fiber layer thickness may represent the neuroprotective effect of cannabis: an optical coherence tomography study

A Kalenderoglu, MH Orum, AS Karadag… - Journal of addictive …, 2020 - Taylor & Francis
Although optical coherence tomography (OCT) has been used in many neuropsychiatric
disorders, data on substance use disorders (SUD) are not available. The aim of this study …

Human ecstasy use is associated with increased cortical excitability: an fMRI study

AL Bauernfeind, MS Dietrich, JU Blackford… - …, 2011 - nature.com
Abstract The serotonergic neurotoxin, 3, 4-methylenedioxymethamphetamine
(MDMA/Ecstasy), is a highly popular recreational drug. Human recreational MDMA users …

N-acetylaspartate (NAA) correlates inversely with cannabis use in a frontal language processing region of neocortex in MDMA (Ecstasy) polydrug users: a 3 T …

RL Cowan, JM Joers, MS Dietrich - Pharmacology Biochemistry and …, 2009 - Elsevier
Impaired verbal memory is common in MDMA (Ecstasy) polydrug users. The contributions of
Ecstasy or polydrug exposure to reduced verbal memory are unclear, as is the neural basis …