Rational design of metalloenzymes: From single to multiple active sites

YW Lin - Coordination Chemistry Reviews, 2017 - Elsevier
Artificial metalloenzymes combine the advantages of both natural enzymes and chemically
synthesized models, which have achieved significant progress in the last decade. This …

Noncanonical Amino Acids: Bringing New-to-Nature Functionalities to Biocatalysis

B Brouwer, F Della-Felice, JH Illies… - Chemical …, 2024 - ACS Publications
Biocatalysis has become an important component of modern organic chemistry, presenting
an efficient and environmentally friendly approach to synthetic transformations. Advances in …

An artificial heme enzyme for cyclopropanation reactions

L Villarino, KE Splan, E Reddem… - Angewandte Chemie …, 2018 - Wiley Online Library
An artificial heme enzyme was created through self‐assembly from hemin and the
lactococcal multidrug resistance regulator (LmrR). The crystal structure shows the heme …

The effect of oxygenated fuel properties on diesel spray combustion and soot formation

W Park, S Park, RD Reitz, E Kurtz - Combustion and Flame, 2017 - Elsevier
Diesel engines have advantages due to their potential for high fuel conversion efficiency.
However, it is necessary to reduce pollutant emissions, particularly NOx and soot to meet …

Biodegradation of aromatic pollutants by metalloenzymes: A structural-functional-environmental perspective

YW Lin - Coordination chemistry reviews, 2021 - Elsevier
Environmental security is closely related to public health. Aromatic pollutants constitute a
class of hazardous environmental chemicals, such as halophenols and polycyclic aromatic …

Structure and function of heme proteins regulated by diverse post-translational modifications

YW Lin - Archives of biochemistry and biophysics, 2018 - Elsevier
Heme proteins are crucial for biological systems by performing diverse functions. Nature has
evolved diverse approaches to fine-tune the structure and function of heme proteins, of …

Uranyl binding to proteins and structural-functional impacts

YW Lin - Biomolecules, 2020 - mdpi.com
The widespread use of uranium for civilian purposes causes a worldwide concern of its
threat to human health due to the long-lived radioactivity of uranium and the high toxicity of …

Design of artificial metalloproteins/metalloenzymes by tuning noncovalent interactions

S Hirota, YW Lin - JBIC Journal of Biological Inorganic Chemistry, 2018 - Springer
Noncovalent weak interactions [hydrophobic interaction and hydrogen (H)-bond] play crucial
roles in controlling the functions of biomolecules, and thus have been used to design …

Uncovering the origins of dog–human eye contact: dingoes establish eye contact more than wolves, but less than dogs

AM Johnston, C Turrin, L Watson, AM Arre, LR Santos - Animal Behaviour, 2017 - Elsevier
Highlights•We provide new evidence about how dog–human eye contact evolved.•Unlike
wolves, nearly all dingoes initiated eye contact with a familiar human.•However, the duration …

Rational design of artificial metalloproteins and metalloenzymes with metal clusters

YW Lin - Molecules, 2019 - mdpi.com
Metalloproteins and metalloenzymes play important roles in biological systems by using the
limited metal ions, complexes, and clusters that are associated with the protein matrix. The …