Background We have previously reported successful induction of renal allograft tolerance in
nonhuman primates (NHP) after an initial posttransplant period of conventional …

The hemostatic balance in patients with liver diseases is relatively well preserved due to
concomitant alterations in pro-and antihemostatic pathways. Thrombin generation studies …

Background and Aim Patients with cirrhosis may acquire profound changes in haemostasis.
Although haemostatic changes in cirrhosis have been extensively studied, most studies …

BACKGROUND Orthotopic liver transplantation is associated with a risk of bleeding.
Coagulation in cirrhotic patients is difficult to assess with standard coagulation tests because …

Background & Aims Non-alcoholic fatty liver disease (NAFLD) is associated with an
increased risk of thrombosis. However, it remains unclear if hypercoagulability contributes to …

We hypothesized that preemptive fibrinogen administration to obtain an initial plasma level
of 2.9 g/L would reduce transfusion requirements in liver transplantation. A randomized …

Patients with cirrhosis frequently acquire profound hemostatic alterations, which may affect
thrombus quality and composition—factors that determine the susceptibility to embolization …

Thrombocytopenia is common in chronic and acute liver failure and platelet function as
assessed by suspension aggregometry, PFA-100 (Siemens Healthcare, germany), or …

Background & Aims A simultaneous decline in pro‐and anticoagulant drivers in patients with
liver diseases results in a “rebalanced” haemostatic system, even in acutely ill patients …

Patients undergoing liver transplantation have complex changes in their hemostatic system,
and the net effect of these changes appears to be a “rebalanced” hemostatic profile …