Organelle-targeted photosensitizers for precision photodynamic therapy

R Wang, X Li, J Yoon - ACS Applied Materials & Interfaces, 2021 - ACS Publications
Subcellular organelles are the cornerstones of cells, and destroying them will cause cell
dysfunction and even death. Therefore, realizing precise organelle targeting of …

Photodynamic therapy (PDT) of cancer: from local to systemic treatment

JM Dąbrowski, LG Arnaut - Photochemical & Photobiological Sciences, 2015 - pubs.rsc.org
Photodynamic therapy (PDT) requires a medical device, a photosensitizing drug and
adequate use of both to trigger biological mechanisms that can rapidly destroy the primary …

Graphene-based nanosheets for delivery of chemotherapeutics and biological drugs

G Shim, MG Kim, JY Park, YK Oh - Advanced drug delivery reviews, 2016 - Elsevier
Abstract Graphene-based nanosheets (GNS), including graphenes, graphene oxides and
reduced graphene oxides, have properties suitable for delivery of various molecules. With …

Manipulation of Mitophagy by “All-in-One” nanosensitizer augments sonodynamic glioma therapy

F Qu, P Wang, K Zhang, Y Shi, Y Li, C Li, J Lu, Q Liu… - Autophagy, 2020 - Taylor & Francis
Limited penetration of chemotherapeutic drugs through the blood brain barrier (BBB), and
the increased chemo-resistance of glioma cells due to macroautophagy/autophagy, result in …

Reactive oxygen species in photodynamic therapy: mechanisms of their generation and potentiation

JM Dąbrowski - Advances in inorganic chemistry, 2017 - Elsevier
Reactive oxygen species (ROS) play key roles in cell signaling systems and homeostasis,
and they are also fundamental to photodynamic therapy (PDT). PDT efficacy can be affected …

Gold nanoclusters‐based nanoprobes for simultaneous fluorescence imaging and targeted photodynamic therapy with superior penetration and retention behavior in …

C Zhang, C Li, Y Liu, J Zhang, C Bao… - Advanced Functional …, 2015 - Wiley Online Library
Gold nanoclusters (GNCs) attract increasing attention due to their potential applications in
sensing, catalysis, optoelectronics, and biomedicine. Herein, the formation of highly …

Decoupling theranostics with rare earth doped nanoparticles

A Skripka, V Karabanovas, G Jarockyte… - Advanced Functional …, 2019 - Wiley Online Library
Theranostic nanoagents targeted for personalized medicine provide a unified platform for
therapeutics and diagnostics. To be able to discretely control each individually, allows for …

[HTML][HTML] Enhancing photodynamic therapy of refractory solid cancers: Combining second-generation photosensitizers with multi-targeted liposomal delivery

R Weijer, M Broekgaarden, M Kos, R van Vught… - … of Photochemistry and …, 2015 - Elsevier
Contemporary photodynamic therapy (PDT) for the last-line treatment of refractory cancers
such as nasopharyngeal carcinomas, superficial recurrent urothelial carcinomas, and non …

[HTML][HTML] Advanced photodynamic therapy with an engineered M13 phage targeting EGFR: Mitochondrial localization and autophagy induction in ovarian cancer cell …

B Bortot, M Apollonio, G Baj, L Andolfi, L Zupin… - Free Radical Biology …, 2022 - Elsevier
Photodynamic therapy (PDT) is a potential synergistic approach to chemotherapy for treating
ovarian cancer, the most lethal gynecologic malignancy. Here we used M13 bacteriophage …

Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents

M Dichiara, O Prezzavento, A Marrazzo, V Pittala… - European Journal of …, 2017 - Elsevier
In the search of novel strategies for the treatment of cancer, photodynamic therapy (PDT)
has emerged as an effective, safe for repeated use, and non-invasive method. This …