Metabolic phenotyping in clinical and surgical environments

JK Nicholson, E Holmes, JM Kinross, AW Darzi… - Nature, 2012 - nature.com
Metabolic phenotyping involves the comprehensive analysis of biological fluids or tissue
samples. This analysis allows biochemical classification of a person's physiological or …

Current and emerging methods for ovarian cancer screening and diagnostics: a comprehensive review

JM Liberto, SY Chen, IM Shih, TH Wang, TL Wang… - Cancers, 2022 - mdpi.com
Simple Summary Ovarian high-grade serous carcinoma (HGSC) has a 5-year survival rate
of less than 50%, making it one of the most lethal gynecological cancers for women in the …

Designed concave octahedron heterostructures decode distinct metabolic patterns of epithelial ovarian tumors

C Pei, Y Wang, Y Ding, R Li, W Shu, Y Zeng… - Advanced …, 2023 - Wiley Online Library
Epithelial ovarian cancer (EOC) is a polyfactorial process associated with alterations in
metabolic pathways. A high‐performance screening tool for EOC is in high demand to …

NMR-based metabolomics in human disease diagnosis: applications, limitations, and recommendations

AHM Emwas, RM Salek, JL Griffin, J Merzaban - Metabolomics, 2013 - Springer
Metabolomics is a dynamic and emerging research field, similar to proteomics,
transcriptomics and genomics in affording global understanding of biological systems. It is …

Can NMR solve some significant challenges in metabolomics?

GAN Gowda, D Raftery - Journal of Magnetic Resonance, 2015 - Elsevier
The field of metabolomics continues to witness rapid growth driven by fundamental studies,
methods development, and applications in a number of disciplines that include biomedical …

Identification of potential biomarkers for ovarian cancer by urinary metabolomic profiling

T Zhang, X Wu, C Ke, M Yin, Z Li, L Fan… - Journal of proteome …, 2013 - ACS Publications
To evaluate the application of urinary metabolomics on discovering potential biomarkers for
epithelial ovarian cancer (EOC), urine samples from 40 preoperative EOC patients, 62 …

Novel personalized pathway-based metabolomics models reveal key metabolic pathways for breast cancer diagnosis

S Huang, N Chong, NE Lewis, W Jia, G Xie… - Genome medicine, 2016 - Springer
Background More accurate diagnostic methods are pressingly needed to diagnose breast
cancer, the most common malignant cancer in women worldwide. Blood-based …

toxicometabolomics

M Bouhifd, T Hartung, HT Hogberg… - Journal of Applied …, 2013 - Wiley Online Library
Metabolomics use in toxicology is rapidly increasing, particularly owing to advances in mass
spectroscopy, which is widely used in the life sciences for phenotyping disease states …

NMR-based metabolomics

GA Nagana Gowda, D Raftery - Cancer Metabolomics: Methods and …, 2021 - Springer
Nuclear magnetic resonance (NMR) spectroscopy is a major analytical method used in the
growing field of metabolomics. Although NMR is relatively less sensitive than mass …

[HTML][HTML] Diagnosis of bladder cancer and prediction of survival by urinary metabolomics

X Jin, SJ Yun, P Jeong, IY Kim, WJ Kim, S Park - Oncotarget, 2014 - ncbi.nlm.nih.gov
Bladder cancer (BC) is a common cancer but diagnostic modalities, such as cystoscopy and
urinary cytology, have limitations. Here, high-performance liquid chromatography …