[HTML][HTML] Role of the NLRP3 inflammasome in autoimmune diseases
Z Li, J Guo, L Bi - Biomedicine & pharmacotherapy, 2020 - Elsevier
NOD-like receptor family pyrin domain containing 3 (NLRP3) is an intracellular receptor that
senses foreign pathogens and endogenous danger signals. It assembles with apoptosis …
senses foreign pathogens and endogenous danger signals. It assembles with apoptosis …
NLRP3 inflammasome: checkpoint connecting innate and adaptive immunity in autoimmune diseases
Y Zhang, W Yang, W Li, Y Zhao - Frontiers in immunology, 2021 - frontiersin.org
Autoimmune diseases are a broad spectrum of human diseases that are characterized by
the breakdown of immune tolerance and the production of autoantibodies. Recently …
the breakdown of immune tolerance and the production of autoantibodies. Recently …
NLRP3: a promising therapeutic target for autoimmune diseases
HH Shen, YX Yang, X Meng, XY Luo, XM Li… - Autoimmunity …, 2018 - Elsevier
NLRP3, a member of nucleotide-binding domain-(NOD) like receptor family, can be found in
large varieties of immune and non-immune cells. Upon activation, the NLRP3, apoptosis …
large varieties of immune and non-immune cells. Upon activation, the NLRP3, apoptosis …
Regulation of the MIR155 host gene in physiological and pathological processes
TS Elton, H Selemon, SM Elton, NL Parinandi - Gene, 2013 - Elsevier
MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in
posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing …
posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing …
MicroRNA-155—at the critical interface of innate and adaptive immunity in arthritis
MicroRNAs (miRNAs) are small non-coding RNAs that fine-tune the cell response to a
changing environment by modulating the cell transcriptome. miR-155 is a multifunctional …
changing environment by modulating the cell transcriptome. miR-155 is a multifunctional …
The oncogenic role of miR-155 in breast cancer
Abstract miR-155 is an oncogenic miRNA with well described roles in leukemia. However,
additional roles of miR-155 in breast cancer progression have recently been described. A …
additional roles of miR-155 in breast cancer progression have recently been described. A …
Impact of microRNAs on ischemic stroke: from pre-to post-disease
G Li, KC Morris-Blanco, MS Lopez, T Yang… - Progress in …, 2018 - Elsevier
Stroke is the number one cause of neurological dysfunction in adults and has a heavy
socioeconomic burden worldwide. The etiological origins of ischemic stroke and resulting …
socioeconomic burden worldwide. The etiological origins of ischemic stroke and resulting …
MicroRNAs regulating oxidative stress and inflammation in relation to obesity and atherosclerosis
M Hulsmans, DD Keyzer, P Holvoet - The FASEB Journal, 2011 - Wiley Online Library
ABSTRACT A primary event in atherogenesis is the infiltration of activated inflammatory cells
into the arterial wall. There they secrete reactive oxygen species and oxidize lipoproteins …
into the arterial wall. There they secrete reactive oxygen species and oxidize lipoproteins …
Mir-155 is overexpressed in systemic sclerosis fibroblasts and is required for NLRP3 inflammasome-mediated collagen synthesis during fibrosis
CM Artlett, S Sassi-Gaha, JL Hope… - Arthritis research & …, 2017 - Springer
Background Despite the important role that microRNAs (miRNAs) play in immunity and
inflammation, their involvement in systemic sclerosis (SSc) remains poorly characterized …
inflammation, their involvement in systemic sclerosis (SSc) remains poorly characterized …
MiR155-5p in adventitial fibroblasts-derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin-converting enzyme …
Proliferation of vascular smooth muscle cells (VSMCs) plays crucial roles in vascular
remodelling and stiffening in hypertension. Vascular adventitial fibroblasts are a key …
remodelling and stiffening in hypertension. Vascular adventitial fibroblasts are a key …