Genetic and epigenetic factors associated with increased severity of Covid‐19
Z Yildirim, OS Sahin, S Yazar… - Cell biology …, 2021 - Wiley Online Library
Since December 2019, a new form of severe acute respiratory syndrome (SARS) from a
novel strain of coronavirus (SARS coronavirus 2 [SARS‐CoV‐2]) has been spreading …
novel strain of coronavirus (SARS coronavirus 2 [SARS‐CoV‐2]) has been spreading …
Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection
The SARS-CoV-2 pandemic has become one of the most serious health concerns globally.
Although multiple vaccines have recently been approved for the prevention of coronavirus …
Although multiple vaccines have recently been approved for the prevention of coronavirus …
The complexity of SARS-CoV-2 infection and the COVID-19 pandemic
MK da Silva Torres, CDA Bichara… - Frontiers in …, 2022 - frontiersin.org
The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) led to the death of millions of people worldwide and thousands more infected individuals …
2) led to the death of millions of people worldwide and thousands more infected individuals …
[HTML][HTML] Structural modelling of SARS-CoV-2 alpha variant (B. 1.1. 7) suggests enhanced furin binding and infectivity
Abstract The B. 1.1. 7 SARS-CoV-2 strain that has emerged in the UK in early December
presents seven mutations and three deletions on S-protein structure that could lead to a …
presents seven mutations and three deletions on S-protein structure that could lead to a …
Cellular and humoral immune responses in covid-19 and immunotherapeutic approaches
A Hasan, E Al-Ozairi, Z Al-Baqsumi… - ImmunoTargets and …, 2021 - Taylor & Francis
Abstract Coronavirus disease 2019 (Covid-19), caused by the novel coronavirus severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can range in severity from …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can range in severity from …
Remdesivir MD simulations suggest a more favourable binding to SARS-CoV-2 RNA dependent RNA polymerase mutant P323L than wild-type
SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) protein is the target for the antiviral
drug Remdesivir (RDV). With RDV clinical trials on COVID-19 patients showing a reduced …
drug Remdesivir (RDV). With RDV clinical trials on COVID-19 patients showing a reduced …
SARS-CoV-2 Susceptibility and ACE2 Gene Variations Within Diverse Ethnic Backgrounds
N Vadgama, A Kreymerman, J Campbell… - Frontiers in …, 2022 - frontiersin.org
There is considerable variability in the susceptibility and progression for COVID-19 and it
appears to be strongly correlated with age, gender, ethnicity and pre-existing health …
appears to be strongly correlated with age, gender, ethnicity and pre-existing health …
Analysis of ACE2 and TMPRSS2 coding variants as a risk factor for SARS‐CoV‐2 from 946 whole‐exome sequencing data in the Turkish population
Heterogeneity in symptoms associated with COVID‐19 in infected patients remains unclear.
ACE2 and TMPRSS2 gene variants are considered possible risk factors for COVID‐19. In …
ACE2 and TMPRSS2 gene variants are considered possible risk factors for COVID‐19. In …
SARS-COV-2 spike binding to ACE2 in living cells monitored by TR-FRET
E Cecon, M Burridge, L Cao, L Carter… - Cell Chemical …, 2022 - cell.com
Targeting the interaction between the SARS-CoV-2 spike protein and human ACE2, its
primary cell membrane receptor, is a promising therapeutic strategy to prevent viral entry …
primary cell membrane receptor, is a promising therapeutic strategy to prevent viral entry …
Discovery of natural products to block SARS-CoV-2 S-protein interaction with Neuropilin-1 receptor: A molecular dynamics simulation approach
Abstract Neuropilin-1 (NRP1) is a widely expressed cell surface receptor protein
characterized by its pleiotropic function. Recent reports highlighted NRP1 as an additional …
characterized by its pleiotropic function. Recent reports highlighted NRP1 as an additional …