Hydrogel‐based growth factor delivery platforms: strategies and recent advances

BH Shan, FG Wu - Advanced Materials, 2024 - Wiley Online Library
Growth factors play a crucial role in regulating a broad variety of biological processes and
are regarded as powerful therapeutic agents in tissue engineering and regenerative …

New insights of scaffolds based on hydrogels in tissue engineering

DM Radulescu, IA Neacsu, AM Grumezescu… - Polymers, 2022 - mdpi.com
In recent years, biomaterials development and characterization for new applications in
regenerative medicine or controlled release represent one of the biggest challenges. Tissue …

[HTML][HTML] Injectable hydrogels in central nervous system: Unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering

E Hasanzadeh, A Seifalian, A Mellati, J Saremi… - Materials Today Bio, 2023 - Elsevier
Repairing central nervous system (CNS) is difficult due to the inability of neurons to recover
after damage. A clinically acceptable treatment to promote CNS functional recovery and …

Hyaluronic acid biomaterials for central nervous system regenerative medicine

G Jensen, JL Holloway, SE Stabenfeldt - Cells, 2020 - mdpi.com
Hyaluronic acid (HA) is a primary component of the brain extracellular matrix and functions
through cellular receptors to regulate cell behavior within the central nervous system (CNS) …

[HTML][HTML] Functional hydrogels as therapeutic tools for spinal cord injury: New perspectives on immunopharmacological interventions

CM Walsh, JK Wychowaniec, DF Brougham… - Pharmacology & …, 2022 - Elsevier
Spinal cord injury (SCI) is a complex medical and psychological challenge for which there is
no curative therapy currently available. Despite major progress in pharmacological and …

[HTML][HTML] Injectable hydrogels for spinal cord injury repair

H Wang, H Zhang, Z Xie, K Chen, M Ma, Y Huang… - Engineered …, 2022 - Elsevier
Spinal cord injury (SCI) often causes severe functional impairment of body, which leads to a
huge burden to the patient and the whole society. Many strategies, especially biomaterials …

Regulating endogenous neural stem cell activation to promote spinal cord injury repair

EAB Gilbert, N Lakshman, KSK Lau, CM Morshead - Cells, 2022 - mdpi.com
Spinal cord injury (SCI) affects millions of individuals worldwide. Currently, there is no cure,
and treatment options to promote neural recovery are limited. An innovative approach to …

[HTML][HTML] The dynamic inflammatory tissue microenvironment: Signality and disease therapy by biomaterials

R Mata, Y Yao, W Cao, J Ding, T Zhou, Z Zhai, C Gao - Research, 2021 - spj.science.org
Tissue regeneration is an active multiplex process involving the dynamic inflammatory
microenvironment. Under a normal physiological framework, inflammation is necessary for …

Recent trends in the development of peptide and protein-based hydrogel therapeutics for the healing of CNS injury

N Mukherjee, A Adak, S Ghosh - Soft Matter, 2020 - pubs.rsc.org
Traumatic brain injury (TBI) and spinal cord injury (SCI) cause millions of deaths and
permanent or prolonged physical disabilities around the globe every year. It generally …

Polysaccharide-based hydrogels for microencapsulation of stem cells in regenerative medicine

SY Lee, J Ma, TS Khoo, N Abdullah… - … in Bioengineering and …, 2021 - frontiersin.org
Stem cell-based therapy appears as a promising strategy to induce regeneration of
damaged and diseased tissues. However, low survival, poor engraftment and a lack of site …