Sex differences in anxiety disorders: interactions between fear, stress, and gonadal hormones

LY Maeng, MR Milad - Hormones and behavior, 2015 - Elsevier
This article is part of a Special Issue “SBN 2014”. Women are more vulnerable to stress-and
fear-based disorders, such as anxiety and post-traumatic stress disorder. Despite the …

Sex: a significant risk factor for neurodevelopmental and neurodegenerative disorders

P Pinares-Garcia, M Stratikopoulos, A Zagato, H Loke… - Brain sciences, 2018 - mdpi.com
Males and females sometimes significantly differ in their propensity to develop neurological
disorders. Females suffer more from mood disorders such as depression and anxiety …

PTSD and sexual dysfunction in men and women

R Yehuda, AMY Lehrner… - The journal of sexual …, 2015 - academic.oup.com
Introduction Difficulties in sexual desire and function often occur in persons with
posttraumatic stress disorder (PTSD), but many questions remain regarding the mechanisms …

Mechanisms of estradiol in fear circuitry: implications for sex differences in psychopathology

KK Cover, LY Maeng, K Lebrón-Milad… - Translational …, 2014 - nature.com
Over the past two decades, substantial knowledge has been attained about the mechanisms
underlying the acquisition and subsequent extinction of conditioned fear. Knowledge gained …

Sex differences in fear extinction

ER Velasco, A Florido, MR Milad, R Andero - … & Biobehavioral Reviews, 2019 - Elsevier
Despite the exponential increase in fear research during the last years, few studies have
included female subjects in their design. The need to include females arises from the …

Gender specific differences in disease susceptibility: the role of epigenetics

L Migliore, V Nicoli, A Stoccoro - Biomedicines, 2021 - mdpi.com
Many complex traits or diseases, such as infectious and autoimmune diseases, cancer,
xenobiotics exposure, neurodevelopmental and neurodegenerative diseases, as well as the …

The neurobiological basis of sex differences in learned fear and its inhibition

HLL Day, CW Stevenson - European Journal of Neuroscience, 2020 - Wiley Online Library
Learning that certain cues or environments predict threat enhances survival by promoting
appropriate fear and the resulting defensive responses. Adapting to changing stimulus …

Sex differences in depression and anxiety

P Pavlidi, N Kokras, C Dalla - Sex Differences in Brain Function and …, 2022 - Springer
Depression and anxiety disorders carry a tremendous worldwide burden and emerge as a
significant cause of disability among western societies. Both disorders are known to …

Prenatal exposure to DEHP induces neuronal degeneration and neurobehavioral abnormalities in adult male mice

R Barakat, PC Lin, CJ Park… - Toxicological …, 2018 - academic.oup.com
Phthalates are a family of synthetic chemicals that are used in producing a variety of
consumer products. Di-(2-ethylhexyl) phthalate (DEHP) is an widely used phthalate and …

Centella Asiatica Improves Memory and Promotes Antioxidative Signaling in 5XFAD Mice

DG Matthews, M Caruso, CF Murchison, JY Zhu… - Antioxidants, 2019 - mdpi.com
Centella asiatica (CA) herb is a traditional medicine, long reputed to provide cognitive
benefits. We have reported that CA water extract (CAW) treatment improves cognitive …