GABAergic interneurons in the neocortex: from cellular properties to circuits

R Tremblay, S Lee, B Rudy - Neuron, 2016 - cell.com
Cortical networks are composed of glutamatergic excitatory projection neurons and local
GABAergic inhibitory interneurons that gate signal flow and sculpt network dynamics …

Three groups of interneurons account for nearly 100% of neocortical GABAergic neurons

B Rudy, G Fishell, SH Lee… - Developmental …, 2011 - Wiley Online Library
An understanding of the diversity of cortical GABAergic interneurons is critical to understand
the function of the cerebral cortex. Recent data suggest that neurons expressing three …

Cortex is driven by weak but synchronously active thalamocortical synapses

RM Bruno, B Sakmann - Science, 2006 - science.org
Sensory stimuli reach the brain via the thalamocortical projection, a group of axons thought
to be among the most powerful in the neocortex. Surprisingly, these axons account for …

Supralinear increase of recurrent inhibition during sparse activity in the somatosensory cortex

C Kapfer, LL Glickfeld, BV Atallah, M Scanziani - Nature neuroscience, 2007 - nature.com
The balance between excitation and inhibition in the cortex is crucial in determining sensory
processing. Because the amount of excitation varies, maintaining this balance is a dynamic …

Neocortical layer 6, a review

AM Thomson - Frontiers in neuroanatomy, 2010 - frontiersin.org
This review attempts to summarise some of the major areas of neocortical research as it
pertains to layer 6. After a brief summary of the development of this intriguing layer, the …

Neural coding during active somatosensation revealed using illusory touch

DH O'connor, SA Hires, ZV Guo, N Li, J Yu… - Nature …, 2013 - nature.com
Active sensation requires the convergence of external stimuli with representations of body
movements. We used mouse behavior, electrophysiology and optogenetics to dissect the …

Feedforward mechanisms of excitatory and inhibitory cortical receptive fields

RM Bruno, DJ Simons - Journal of Neuroscience, 2002 - Soc Neuroscience
Excitatory and inhibitory cortical layer IV neurons have distinctive response properties.
Thalamocortical connectivity that may underlie differences was examined using cross …

Dynamics of excitation and inhibition underlying stimulus selectivity in rat somatosensory cortex

WB Wilent, D Contreras - Nature neuroscience, 2005 - nature.com
Neurons in sensory systems respond to stimuli within their receptive fields, but the
magnitude of the response depends on specific stimulus features. In the rodent whisker …

Pathway-, layer-and cell-type-specific thalamic input to mouse barrel cortex

BS Sermet, P Truschow, M Feyerabend, JM Mayrhofer… - elife, 2019 - elifesciences.org
Mouse primary somatosensory barrel cortex (wS1) processes whisker sensory information,
receiving input from two distinct thalamic nuclei. The first-order ventral posterior medial …

‐Dynamic representation of whisker deflection by synaptic potentials in spiny stellate and pyramidal cells in the barrels and septa of layer 4 rat somatosensory cortex

M Brecht, B Sakmann - The Journal of physiology, 2002 - Wiley Online Library
Whole‐cell voltage recordings were made in vivo from excitatory neurons (n= 23) in layer 4
of the barrel cortex in urethane‐anaesthetised rats. Their receptive fields (RFs) for a brief …