Activity-based NIR fluorescent probes based on the versatile hemicyanine scaffold: design strategy, biomedical applications, and outlook
The discovery of a near-infrared (NIR, 650–900 nm) fluorescent chromophore hemicyanine
dye with high structural tailorability is of great significance in the field of detection …
dye with high structural tailorability is of great significance in the field of detection …
Design Principles, Sensing Mechanisms, and Applications of Highly Specific Fluorescent Probes for HOCl/OCl–
D Wu, L Chen, Q Xu, X Chen… - Accounts of chemical …, 2019 - ACS Publications
Conspectus Hypochlorous acid/hypochlorite (HOCl/OCl–), one of the most important
reactive oxygen species (ROS), plays vital roles in various physiological and pathological …
reactive oxygen species (ROS), plays vital roles in various physiological and pathological …
Recent development of chemosensors based on cyanine platforms
The cyanine platforms including cyanine, hemicyanine, and squaraine are good candidates
for developing chemosensors because of their excellent photophysical properties …
for developing chemosensors because of their excellent photophysical properties …
A fast-responsive OFF–ON Near-infrared-II fluorescent probe for in vivo detection of hypochlorous acid in rheumatoid arthritis
P Wu, Y Zhu, L Chen, Y Tian, H Xiong - Analytical Chemistry, 2021 - ACS Publications
Rheumatoid arthritis (RA) is a common chronic autoimmune inflammatory disease, and its
etiology is closely related to the overproduction of hypochlorous acid (HClO). However, early …
etiology is closely related to the overproduction of hypochlorous acid (HClO). However, early …
Development of targetable two-photon fluorescent probes to image hypochlorous acid in mitochondria and lysosome in live cell and inflamed mouse model
Hypochlorous acid (HOCl), as a highly potent oxidant, is well-known as a key “killer” for
pathogens in the innate immune system. Recently, mounting evidence indicates that …
pathogens in the innate immune system. Recently, mounting evidence indicates that …
Recent progress in the development of fluorescent, luminescent and colorimetric probes for detection of reactive oxygen and nitrogen species
X Chen, F Wang, JY Hyun, T Wei, J Qiang… - Chemical Society …, 2016 - pubs.rsc.org
Reactive oxygen (ROS) and nitrogen (RNS) species cause oxidative and nitrosative
stresses, respectively. These stresses are implicated not only in diverse physiological …
stresses, respectively. These stresses are implicated not only in diverse physiological …
Photostable ratiometric pdot probe for in vitro and in vivo imaging of hypochlorous acid
Developing probes for the detection of reactive oxygen species (ROS), a hallmark of many
pathophysiological process, is imperative to both understanding the precise roles of ROS in …
pathophysiological process, is imperative to both understanding the precise roles of ROS in …
Bioanalytical methods for hypochlorous acid detection: Recent advances and challenges
R Zhang, B Song, J Yuan - TrAC Trends in Analytical Chemistry, 2018 - Elsevier
Hypochlorous acid (HOCl), a well-known universal disinfectant in clinical practice, plays
important roles in immune systems of animal and human bodies. For understanding the …
important roles in immune systems of animal and human bodies. For understanding the …
Recent progress in the development of fluorescent probes for the detection of hypochlorous acid
YR Zhang, Y Liu, X Feng, BX Zhao - Sensors and Actuators B: Chemical, 2017 - Elsevier
As one of the reactive oxygen species, hypochlorous acid (HOCl) may be associated with
various diseases. To understand the roles of HOCl in living organism, fluorescent probes for …
various diseases. To understand the roles of HOCl in living organism, fluorescent probes for …
Highly specific and ultrasensitive two-photon fluorescence imaging of native HOCl in lysosomes and tissues based on thiocarbamate derivatives
Hypochlorous acid (HOCl) acts as a weak acid distributed mainly in acidic organelle
lysosomes of phagocytes and plays a crucial role in the immune defense. The elaborate …
lysosomes of phagocytes and plays a crucial role in the immune defense. The elaborate …