Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its …

JC Iatridis, SB Nicoll, AJ Michalek, BA Walter… - The spine journal, 2013 - Elsevier
BACKGROUND CONTEXT: Degeneration and injuries of the intervertebral disc (IVD) result
in large alterations in biomechanical behaviors. Repair strategies using biomaterials can be …

Hydrogel adhesives for generalized wound treatment: Design and applications

M Li, G Pan, H Zhang, B Guo - Journal of Polymer Science, 2022 - Wiley Online Library
Wound refers to the place where human body is injured and ruptured. So, wounds in a
broad sense include not only skin wounds, but also damages of muscle, corneal, heart, and …

Design requirements for annulus fibrosus repair: review of forces, displacements, and material properties of the intervertebral disk and a summary of candidate …

RG Long, OM Torre, WW Hom… - Journal of …, 2016 - asmedigitalcollection.asme.org
There is currently a lack of clinically available solutions to restore functionality to the
intervertebral disk (IVD) following herniation injury to the annulus fibrosus (AF) …

Single and dual crosslinked oxidized methacrylated alginate/PEG hydrogels for bioadhesive applications

O Jeon, JE Samorezov, E Alsberg - Acta biomaterialia, 2014 - Elsevier
A degradable, cytocompatible bioadhesive can facilitate surgical procedures and minimize
patient pain and post-surgical complications. In this study a bioadhesive hydrogel system …

Bioadhesives for musculoskeletal tissue regeneration

S Tarafder, GY Park, J Felix, CH Lee - Acta biomaterialia, 2020 - Elsevier
Natural or synthetic materials designed to adhere to biological components, bioadhesives,
have received significant attention in clinics and surgeries. As a result, there are several …

Self-healing dynamic hydrogel as injectable shock-absorbing artificial nucleus pulposus

A Pérez-San Vicente, M Peroglio, M Ernst… - …, 2017 - ACS Publications
The intervertebral discs (IVDs) provide unique flexibility to the spine and exceptional shock
absorbing properties under impact. The inner core of the IVD, the nucleus pulposus (NP) is …

[HTML][HTML] Rheological properties of hydrogels based on ionic liquids

A Jastram, J Claus, PA Janmey, U Kragl - Polymer Testing, 2021 - Elsevier
Hydrogels, based on polymerized ionic liquids, are increasingly used in the medical and
pharmaceutical industry as implants, drug delivery systems, contact lens material, bone …

Injectable and adhesive hydrogels for dealing with wounds

P Ghandforoushan, N Golafshan… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction The development of wound dressing materials that combine healing properties,
ability to self-repair the material damages, skin-friendly adhesive nature, and competent …

Injectable doubly cross-linked microgels for improving the mechanical properties of degenerated intervertebral discs

AH Milani, AJ Freemont, JA Hoyland… - …, 2012 - ACS Publications
The use of injectable pH-responsive doubly cross-linked microgels (DX microgels) to
improve the mechanical properties of degenerated intervertebral discs is demonstrated for …

Weak hydrogen bonds lead to self-healable and bioadhesive hybrid polymeric hydrogels with mineralization-active functions

L Teng, Y Chen, M Jin, Y Jia, Y Wang… - Biomacromolecules, 2018 - ACS Publications
Hydrogels with self-healing features that can spontaneously repair themselves upon
mechanical damage are increasingly attractive for biomedical applications. Many attempts …