Lentiviral vectors (LVs) are potent tools for the delivery of genes of interest into mammalian
cells and are now commonly utilised within the growing field of cell and gene therapy for the …

In December 1983, a seminal paper appeared on the overexpression of human IFN-β in
insect cells with a genetically engineered baculovirus. The finding that baculoviruses …

Insect-derived baculoviruses have emerged as versatile and safe workhorses of
biotechnology. Baculovirus expression vectors (BEVs) have been applied widely for crop …

Introduction: Lentiviruses are a very potent class of viral vectors for which there is presently a
rapidly growing interest for a number of gene therapy. However, their construction …

In this review background information on the baculovirus-insect cell expression system and
its applications for producing protein subunits and virus-like particles for vaccine and other …

Baculovirus infects insects in nature and is non-pathogenic to humans, but can transduce a
broad range of mammalian and avian cells. Thanks to the biosafety, large cloning capacity …

This review offers the basics of lentiviral vector technologies, their advantages and pitfalls,
and an overview of their use in the field of ophthalmology. First, the description of the global …

Despite the extensive research efforts over the past 25 years that have focused on HIV, there
is still no cure for AIDS. However, tremendous progress in the understanding of the structure …

Lentiviral vectors become more and more famous for the use as gene vector for gene
therapy purposes for the treatment of acquired or inherited diseases. In this review, the …

The advent of advanced therapies in the pharmaceutical industry has moved the spotlight
into virus-like particles and viral vectors produced in cell culture holding great promise in a …