The signal pathways and treatment of cytokine storm in COVID-19
L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …
and is more devastating than any other previous infectious disease. It has affected a …
[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19
JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …
The role of cytokines including interleukin-6 in COVID-19 induced pneumonia and macrophage activation syndrome-like disease
Severe COVID-19 associated pneumonia patients may exhibit features of systemic hyper-
inflammation designated under the umbrella term of macrophage activation syndrome …
inflammation designated under the umbrella term of macrophage activation syndrome …
Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions
The coronavirus disease-19 pandemic (COVID-19), which appeared in China in December
2019 and rapidly spread throughout the world, has forced clinicians and scientists to take up …
2019 and rapidly spread throughout the world, has forced clinicians and scientists to take up …
Recommendations for the management of hemophagocytic lymphohistiocytosis in adults
Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory syndrome
induced by aberrantly activated macrophages and cytotoxic T cells. The primary (genetic) …
induced by aberrantly activated macrophages and cytotoxic T cells. The primary (genetic) …
COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study
JJ Manson, C Crooks, M Naja, A Ledlie… - The Lancet …, 2020 - thelancet.com
Background A subset of patients with severe COVID-19 develop a hyperinflammatory
syndrome, which might contribute to morbidity and mortality. This study explores a specific …
syndrome, which might contribute to morbidity and mortality. This study explores a specific …
COVID-19 gone bad: A new character in the spectrum of the hyperferritinemic syndrome?
S Colafrancesco, C Alessandri, F Conti, R Priori - Autoimmunity reviews, 2020 - Elsevier
The severe form of COVID-19 share several clinical and laboratory features with four entities
gathered under the term “hyperferritinemic syndromes” and including macrophage activation …
gathered under the term “hyperferritinemic syndromes” and including macrophage activation …
Cytokine storm syndrome in coronavirus disease 2019: A narrative review
YM Gao, G Xu, B Wang, BC Liu - Journal of internal medicine, 2021 - Wiley Online Library
Cytokine storm syndrome (CSS) is a critical clinical condition induced by a cascade of
cytokine activation, characterized by overwhelming systemic inflammation …
cytokine activation, characterized by overwhelming systemic inflammation …
Silencing the cytokine storm: the use of intravenous anakinra in haemophagocytic lymphohistiocytosis or macrophage activation syndrome
The term cytokine storm syndromes describes conditions characterised by a life-threatening,
fulminant hypercytokinaemia with high mortality. Cytokine storm syndromes can be genetic …
fulminant hypercytokinaemia with high mortality. Cytokine storm syndromes can be genetic …
Natural killer cell dysfunction and its role in COVID-19
When facing an acute viral infection, our immune systems need to function with finite
precision to enable the elimination of the pathogen, whilst protecting our bodies from …
precision to enable the elimination of the pathogen, whilst protecting our bodies from …