Purpose The emergence of novel psychoactive substances (NPS) has been being a
continuous and evolving problem for more than a decade. Every year, dozens of new …

According to the EU Early Warning System (EWS), synthetic cathinones (SCs) are the
second largest new psychoactive substances (NPS) class, with 162 synthetic cathinones …

Reported herein is a photoredox-catalyzed amination of o-hydroxyarylenaminones with tert-
butyl ((perfluoropyridin-4-yl) oxy) carbamate, a versatile amidyl-radical precursor developed …

New psychoactive stimulants and psychedelics continue to play an important role on the
illicit new psychoactive substance (NPS) market. Designer stimulants and psychedelics both …

Psychostimulants interacting with the dopamine transporter (DAT) can be used illicitly or for
the treatment of specific neuropsychiatric disorders. However, they can also produce severe …

Several new synthetic cathinones, which mimic the effect of classical psychostimulants such
as cocaine or MDMA, have appeared in the global illicit drug market in the last decades. In …

Psychiatric and substance use disorders inflict major public health burdens worldwide. Their
widespread burden is compounded by a dearth of effective treatments, underscoring a dire …

The human serotonin transporter (hSERT) terminates neurotransmission by removing
serotonin (5HT) from the synaptic cleft, an essential process for proper functioning of …

Nowadays, more and more young people want to experience illegal, psychoactive
substances, without knowing the risks of exposure. Besides affecting social life …

A photoredox-catalyzed intermolecular tandem sulfonamination/cyclization of enaminones
was realized by using N-aminopyridinium salts as the sulfonaminated reagents without …