Innovations in deep brain stimulation methodology
AA Kühn, J Volkmann - Movement Disorders, 2017 - Wiley Online Library
Deep brain stimulation is a powerful clinical method for movement disorders that no longer
respond satisfactorily to pharmacological management, but its progress has been hampered …
respond satisfactorily to pharmacological management, but its progress has been hampered …
Closed-loop implantable therapeutic neuromodulation systems based on neurochemical monitoring
Closed-loop or intelligent neuromodulation allows adjustable, personalized
neuromodulation which usually incorporates the recording of a biomarker, followed by …
neuromodulation which usually incorporates the recording of a biomarker, followed by …
Probabilistic mapping of deep brain stimulation: insights from 15 years of therapy
Deep brain stimulation (DBS) depends on precise delivery of electrical current to target
tissues. However, the specific brain structures responsible for best outcome are still debated …
tissues. However, the specific brain structures responsible for best outcome are still debated …
[HTML][HTML] Local neuroanatomical and tract-based proxies of optimal subcallosal cingulate deep brain stimulation
Background Deep brain stimulation of the subcallosal cingulate area (SCC-DBS) is a
promising neuromodulatory therapy for treatment-resistant depression (TRD). Biomarkers of …
promising neuromodulatory therapy for treatment-resistant depression (TRD). Biomarkers of …
Artificial neural network based characterization of the volume of tissue activated during deep brain stimulation
A Chaturvedi, JL Luján… - Journal of neural …, 2013 - iopscience.iop.org
Objective. Clinical deep brain stimulation (DBS) systems can be programmed with
thousands of different stimulation parameter combinations (eg electrode contact (s), voltage …
thousands of different stimulation parameter combinations (eg electrode contact (s), voltage …
Explaining clinical effects of deep brain stimulation through simplified target-specific modeling of the volume of activated tissue
B Mädler, VA Coenen - American Journal of …, 2012 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Although progress has been made in understanding the
optimal anatomic structures as target areas for DBS, little effort has been put into modeling …
optimal anatomic structures as target areas for DBS, little effort has been put into modeling …
Structuro-functional surrogates of response to subcallosal cingulate deep brain stimulation for depression
Subcallosal cingulate deep brain stimulation produces long-term clinical improvement in
approximately half of patients with severe treatment-resistant depression. We hypothesized …
approximately half of patients with severe treatment-resistant depression. We hypothesized …
Effects of antidromic and orthodromic activation of STN afferent axons during DBS in Parkinson's disease: a simulation study
G Kang, MM Lowery - Frontiers in computational neuroscience, 2014 - frontiersin.org
Recent studies suggest that subthalamic nucleus (STN)-Deep Brain Stimulation (DBS) may
exert at least part of its therapeutic effect through the antidromic suppression of pathological …
exert at least part of its therapeutic effect through the antidromic suppression of pathological …
Effect of dispersive conductivity and permittivity in volume conductor models of deep brain stimulation
The aim of this study was to examine the effect of dispersive tissue properties on the volume-
conducted voltage waveforms and volume of tissue activated during deep brain stimulation …
conducted voltage waveforms and volume of tissue activated during deep brain stimulation …
A network model of local field potential activity in essential tremor and the impact of deep brain stimulation
Essential tremor (ET), a movement disorder characterised by an uncontrollable shaking of
the affected body part, is often professed to be the most common movement disorder …
the affected body part, is often professed to be the most common movement disorder …