A comprehensive investigation of interactions between antipsychotic drug quetiapine and human serum albumin using multi-spectroscopic, biochemical, and …

S Zargar, TA Wani, NA Alsaif, AIA Khayyat - Molecules, 2022 - mdpi.com
Quetiapine (QTP) is a short-acting atypical antipsychotic drug that treats schizophrenia or
manic episodes of bipolar disorder. Human serum albumin (HSA) is an essential transport …

Nanomaterials as carriers to improve the photodynamic antibacterial therapy

H Liu, Y Jiang, Z Wang, L Zhao, Q Yin, M Liu - Frontiers in Chemistry, 2022 - frontiersin.org
The main treatment for bacterial infections is antibiotic therapy, but the emergence of
bacterial resistance has severely limited the efficacy of antibiotics. Therefore, another …

NBS-Promoted Synthesis of Thiocyanated Aminomaleimides and Site-Selective Intramolecular Cyclization Access to 1, 4-Benzothiazepines via S–CN Bond Cleavage

Q Yang, S Huang, L Yin, Z Wang, X Chen… - The Journal of Organic …, 2024 - ACS Publications
A transition metal-free concise and efficient protocol for the synthesis of thiocyanated
aminomaleimides and benzo [e][1, 4] thiazepine derivatives has been developed. The …

Quetiapine Albumin Nanoparticles as an Efficacious Platform for Brain Deposition and Potentially Improved Antipsychotic Activity

HM Abdel-Bar, AS Tulbah, HW Darwish, R Salama… - Pharmaceutics, 2023 - mdpi.com
Quetiapine (QP) is a second-generation short-acting antipsychotic drug extensively
metabolized in the liver, producing pharmacologically inactive metabolites and leading to …

Photochemical Degradation and In-Silico Studies of Venlafaxine: A Photosensitizing Antidepressant Drug

MB Alshammari, A Ahmad, A Gupta, Q Zia… - Arabian Journal for …, 2024 - Springer
The photochemical behavior of the phototoxic antidepressant drug venlafaxine (VLF, 1) was
studied under aerobic conditions in UV-A light. Irradiation of a phosphate buffer solution of …

Photoinduced electron transfer photodecomposition of 1, 4-Dihydropyridine derivative phototoxic drug Manidipine, Docking and Molecular Dynamic studies

SK Mustafa, M Al-Anazi, MMH Aljohani, N Omer… - 2024 - researchsquare.com
The present investigation focuses on the photochemical transformation of Manidipine (1)
using ultraviolet-A light while being accompanied by an electron-donating agent (Et 3 N) …