Drug retention and stability of solid lipid nanoparticles containing azidothymidine palmitate after autoclaving, storage and lyophilization

H Heiati, R Tawashi, NC Phillips - Journal of microencapsulation, 1998 - Taylor & Francis
Solid lipid nanoparticles (SLNs) were prepared using trilaurine (TL) as the SLN core and
phospholipid (PL) as coating. Neutral and negatively charged PLs werc used to produce …

[图书][B] Temperature and toxicology: an integrative, comparative, and environmental approach

CJ Gordon - 2005 - taylorfrancis.com
Thermoregulation is vital for survival but the interplay between toxic insults and
thermoregulatory mechanisms is often poorly understood. Temperature and Toxicology: An …

Influence of cationic lipids on the stability and membrane properties of paclitaxel‐containing liposomes

RB Campbell, SV Balasubramanian… - Journal of …, 2001 - Elsevier
Paclitaxel (taxol) is a poorly soluble anticancer agent that is in widespread clinical use.
Liposomes provide a less toxic vehicle for solubilizing the drug and increasing the …

Amelioration of Prallethrin‐Induced Oxidative Stress and Hepatotoxicity in Rat by the Administration of Origanum majorana Essential Oil

ATH Mossa, AA Refaie, A Ramadan… - BioMed research …, 2013 - Wiley Online Library
This study was carried out to evaluate the adverse effects of exposure to prallethrin on
oxidant/antioxidant status and liver dysfunction biomarkers and the protective role of …

Oxidative stress induced by lambda-cyhalothrin (LTC) in rat erythrocytes and brain: attenuation by vitamin C

H Fetoui, EM Garoui, F Makni-Ayadi… - Environmental Toxicology …, 2008 - Elsevier
The objective of this study was to investigate the propensity of lambda-cyhalothrin (LTC) to
induce oxidative stress in blood and brain of male Wistar rats and its possible attenuation by …

[HTML][HTML] Phospholipid-cationic lipid interactions: influences on membrane and vesicle properties

RB Campbell, SV Balasubramanian… - Biochimica et Biophysica …, 2001 - Elsevier
Liposomes composed of synthetic dialkyl cationic lipids and zwitterionic phospholipids such
as dioleoylphosphatidylethanolamine have been studied extensively as vehicles for gene …

Taxol-lipid interactions: taxol-dependent effects on the physical properties of model membranes

SV Balasubramanian, RM Straubinger - Biochemistry, 1994 - ACS Publications
Revised Manuscript Received May 10, 1994® abstract: Taxol (paclitaxel) is a diterpenoid
anticancer agent undergoing intensive human clinical evaluation. The pooraqueous …

Cypermethrin-induced plasma membrane perturbation on erythrocytes from rats: reduction of fluidity in the hydrophobic core and in glutathione peroxidase activity

R Gabbianelli, G Falcioni, C Nasuti, F Cantalamessa - Toxicology, 2002 - Elsevier
The effects of treatment with the synthetic insecticide cypermethrin on plasma membrane
fluidity, lipid peroxidation and antioxidant status in rat erythrocytes were investigated. Rats …

Morphological and biochemical perturbations in rat erythrocytes following in vitro exposure to Fenvalerate and its metabolite

K Prasanthi, PS Rajini - Toxicology in Vitro, 2005 - Elsevier
Erythrocytes are a convenient model to understand the membrane oxidative damage
induced by various xenobiotic-prooxidants. In this investigation, we have examined the …

[HTML][HTML] Development and characterization of magnetic cationic liposomes for targeting tumor microvasculature

S Dandamudi, RB Campbell - Biochimica et Biophysica Acta (BBA) …, 2007 - Elsevier
Cationic liposomes preferentially target tumor vasculature compared to vessels in normal
tissues. The distribution of cationic liposomes along vascular networks is, however, patchy …