Lipid droplets are cytoplasmic organelles that store neutral lipids and are critically important
for energy metabolism. Their function in energy storage is firmly established and …

Interferon-stimulated gene (ISG) products take on a number of diverse roles. Collectively,
they are highly effective at resisting and controlling pathogens. In this review, we begin by …

Lipid droplets are the intracellular sites for neutral lipid storage. They are critical for lipid
metabolism and energy homeostasis, and their dysfunction has been linked to many …

Flaviviruses such as dengue (DENV), yellow fever (YFV), West Nile (WNV), and Zika (ZIKV)
are human pathogens of global significance. In particular, DENV causes the most prevalent …

Most cells respond to viral infections by activating innate immune pathways that lead to the
induction of antiviral restriction factors. One such factor, viperin, was discovered almost two …

Viral infection of the cell is able to initiate a signaling cascade of events that ultimately
attempts to limit viral replication and prevent escalating infection through expression of host …

Lipids are essential components for life. Their various structural and physical properties
influence diverse cellular processes and, thereby, human health. Lipids are not genetically …

Lipid droplets (LDs) are increasingly recognized as critical organelles in signalling events,
transient protein sequestration and inter-organelle interactions. However, the role LDs play …

Flaviviruses are emerging arthropod-borne pathogens that cause life-threatening diseases
such as yellow fever, dengue, West Nile encephalitis, tick-borne encephalitis, Kyasanur …

Flaviviruses are arthropod-borne viruses that constitute a major global health problem, with
millions of human infections annually. Their pathogenesis ranges from mild illness to severe …