In all domains of life, genomes contain epigenetic information superimposed over the
nucleotide sequence. Epigenetic signals control DNA–protein interactions and can cause …

Like many eukaryotes, bacteria make widespread use of postreplicative DNA methylation for
the epigenetic control of DNA-protein interactions. Unlike eukaryotes, however, bacteria use …

Summary DNA N 6-methyladenine (6mA) modification is commonly found in microbial
genomes and plays important functions in regulating numerous biological processes in …

The fast-growing Gram-negative bacterium Vibrio natriegens is an attractive microbial
system for molecular biology and biotechnology due to its remarkably short generation time …

N6-methyl-adenine is found in the genomes of bacteria, archaea, protists and fungi. Most
bacterial DNA adenine methyltransferases are part of restriction–modification systems …

Epigenetics is a change in gene expression that is heritable without a change in DNA
sequence itself. This phenomenon is well studied in eukaryotes, particularly in humans for …

The discovery of antibiotics in the last century is considered one of the most important
achievements in the history of medicine. Antibiotic usage has significantly reduced morbidity …

Background. Based on the organization of 10 amino acid domains present in MTases, Dam
is classified in the α group (Fig. 1)(46). Dam homologues are widespread among enteric …

Contrary to mammalian DNA, which is thought to contain only 5‐methylcytosine (m5C),
bacterial DNA contains two additional methylated bases, namely N6‐methyladenine (m6A) …

The DNA adenine methyltransferase (Dam methylase) of Gammaproteobacteria and the cell
cycle-regulated methyltransferase (CcrM) methylase of Alphaproteobacteria catalyze an …