Metal complexes have demonstrated significant antitumor activities and platinum complexes
are well established in the clinical application of cancer chemotherapy. However, the …

The gold drugs, gold sodium thiomalate (Myocrisin), aurothioglucose (Solganal), and the
orally administered auranofin (Ridaura), are utilized in modern medicine for the treatment of …

Gold complexes have recently gained increasing attention in the design of new metal-based
anticancer therapeutics. Gold (III) complexes are generally reactive/unstable under …

The clinical success of platinum-based chemotherapeutic agents was of enormous impact
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …

Metallodrugs offer potential for unique mechanisms of drug action based on the choice of
the metal, its oxidation state, the types and number of coordinated ligands and the …

The discovery of cisplatin's antitumor activity in 1969 prompted the search for novel metal-
containing complexes as potential anticancer drugs. Among these novel complexes, metal N …

The diversity of elements among US Food and Drug Administration (FDA) approved
pharmaceuticals is analyzed and reported, with a focus on atoms other than carbon …

A new era of metal-based drugs started in the 1960s, heralded by the discovery of potent
platinum-based complexes, commencing with cisplatin [(H3N) 2PtCl2], which are effective …

The application of gold in medicine is traceable for several thousand years and Au (i)
compounds have been used clinically to treat rheumatoid arthritis since the last century …

Symmetrical protein cages have evolved to fulfil diverse roles in nature, including
compartmentalization and cargo delivery, and have inspired synthetic biologists to create …