Membrane permeabilizing peptides (MPPs) are as ubiquitous as the lipid bilayer
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …

Distance distributions between paramagnetic centers in the range of 1.8 to 6 nm in
membrane proteins and up to 10 nm in deuterated soluble proteins can be measured by the …

The threat of a worldwide influenza pandemic has greatly increased over the past decade
with the emergence of highly virulent avian influenza strains. The increased frequency of …

Polyhexamethylene biguanide (PHMB) is a cationic polymer with antimicrobial and antiviral
properties. It has been commonly accepted that the antimicrobial activity is due to the ability …

Applications of distance measurements by pulse dipolar electron-paramagnetic resonance
(PD-EPR) spectroscopy to structural biology are based on introducing spin labels (SLs) at …

We present the measurement of Cu2+− Cu2+ and Cu2+− nitroxide distance distributions
using double electron− electron resonance (DEER) on a proline-based peptide and an …

To study the interaction between melittin peptides and lipid bilayer, we performed coarse-
grained simulations on systems containing melittin interacting with a bilayer containing …

Distance determination, by pulse EPR techniques, between two spin labels attached to
biomolecules has become an attractive methodology to probe conformations and …

Interactions of the presynaptic protein α-synuclein with membranes are involved in its
physiological action as well as in the pathological misfolding and aggregation related to …

The prototypical antimicrobial peptide, melittin, is well-known for its ability to induce pores in
zwitterionic model lipid membranes. However, the mechanism by which melittin …