Biomarkers of sepsis: time for a reappraisal

C Pierrakos, D Velissaris, M Bisdorff, JC Marshall… - Critical Care, 2020 - Springer
Introduction Sepsis biomarkers can have important diagnostic, therapeutic, and prognostic
functions. In a previous review, we identified 3370 references reporting on 178 different …

Diagnosing and managing sepsis by probing the host response to infection: advances, opportunities, and challenges

IL Gunsolus, TE Sweeney, O Liesenfeld… - Journal of clinical …, 2019 - Am Soc Microbiol
Sepsis is a major source of mortality and morbidity globally. Accurately diagnosing sepsis
remains challenging due to the heterogeneous nature of the disease, and delays in …

Predicting mortality in adult patients with sepsis in the emergency department by using combinations of biomarkers and clinical scoring systems: a systematic review

K Tong-Minh, I Welten, H Endeman… - BMC emergency …, 2021 - Springer
Background Sepsis can be detected in an early stage in the emergency department (ED) by
biomarkers and clinical scoring systems. A combination of multiple biomarkers or biomarker …

Early discharge from the emergency department based on soluble urokinase plasminogen activator receptor (suPAR) levels: a TRIAGE III substudy

M Schultz, LJH Rasmussen, T Høi-Hansen… - Disease …, 2019 - Wiley Online Library
Objective. Using biomarkers for early and accurate identification of patients at low risk of
serious illness may improve the flow in the emergency department (ED) by classifying these …

Availability of suPAR in emergency departments may improve risk stratification: a secondary analysis of the TRIAGE III trial

M Schultz, LJH Rasmussen, T Kallemose… - Scandinavian Journal of …, 2019 - Springer
Introduction Soluble urokinase plasminogen activator receptor (suPAR) is a prognostic and
nonspecific biomarker associated with short-term mortality in emergency department (ED) …

Elevated suPAR is an independent risk marker for incident kidney disease in acute medical patients

E Iversen, MB Houlind, T Kallemose… - Frontiers in Cell and …, 2020 - frontiersin.org
Introduction Identifying patients at high risk of developing kidney disease could lead to early
clinical interventions that prevent or slow disease progression. Soluble urokinase …

[HTML][HTML] Soluble urokinase plasminogen activator receptor (suPAR) in the emergency department: An update

D Velissaris, N Zareifopoulos… - Caspian Journal of …, 2022 - ncbi.nlm.nih.gov
Background: The biomarker soluble urokinase plasminogen activator receptor (suPAR) is an
indicator of inflammation which is increased in a variety of chronic and acute disease states …

The use of soluble urokinase plasminogen activator receptor (suPAR) as a marker of sepsis in the emergency department setting. A current review

D Velissaris, C Pierrakos, V Karamouzos… - Acta Clinica …, 2021 - Taylor & Francis
Aim: The purpose of this review is to summarize all relevant publications regarding the use
and validity of the soluble urokinase plasminogen activator receptor (suPAR) when used by …

Risk assessment models for potential use in the emergency department have lower predictive ability in older patients compared to the middle-aged for short-term …

M Schultz, LJH Rasmussen, N Carlson… - BMC geriatrics, 2019 - Springer
Background Older patients is a complex group at increased risk of adverse outcomes
compared to younger patients, which should be considered in the risk assessment …

Overall and inter‐individual effect of four different drug classes on soluble urokinase plasminogen activator receptor in type 1 and type 2 diabetes

V Rotbain Curovic, MB Houlind… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aim To evaluate the effect of four different drug classes on soluble urokinase plasminogen
activator receptor (suPAR), a biomarker active in multiple inflammatory processes and a risk …