Matrix metalloproteinases (MMPs) are the major protease family responsible for the
cleavage of the matrisome (global composition of the extracellular matrix (ECM) proteome) …

Bone-forming cells originate from distinct embryological layers, mesoderm (axial and
appendicular bones) and ectoderm (precursor of neural crest cells, which mainly form facial …

Bone development and healing processes involve a complex cascade of biological events
requiring well-orchestrated synergism with bone cells, growth factors, and other trophic …

Abstract Background Matrix metalloproteinases (MMPs) not only work as enzymes but also
as degrading enzymes that have been shown to play an important function in extracellular …

OBJECTIVE: The objective of this study was to determine the expression of matrix
metalloproteinase-2 (MMP-2) and-9 (MMP-9) during apical periodontitis development …

Objectives: In regenerative medicine, surface engineering of bioinert synthetic materials is
often required in order to introduce bioactive species that can promote cell adhesion …

Background Biofunctionalization of titanium surfaces can improve host responses,
especially considering the time for osteointegration and patient recovery. This prompted us …

INTRODUCTION: The aim of this study was to compare the gelatinolytic activity of matrix
metalloproteinase (MMP)-2 and MMP-9 and the expression of tissue inhibitor of matrix …

Signal transduction involves studying the intracellular mechanisms that govern cellular
responses to external stimuli such as hormones, cytokines, and also cell adhesion to …

Large bone defects represent major clinical problems in the practice of reconstructive
orthopedic and craniofacial surgery. The aim of this study was to examine, through …