Efficient iron acquisition is critical for an invading microbe's survival and virulence. Most of
the iron in mammals is incorporated into heme, which can be plundered by certain bacterial …

Iron is essential for the survival of most bacteria but presents a significant challenge given its
limited bioavailability. Furthermore, the toxicity of iron combined with the need to maintain …

Active nutrient uptake is fundamental for survival and pathogenicity of Gram-negative
bacteria, which operate a multi-protein Ton system to transport essential nutrients like metals …

Abstract Background Methanobactins (Mbns) are a family of copper-binding natural products
involved in copper uptake by methanotrophic bacteria. The few Mbns that have been …

Isothermal titration calorimetry (ITC) is a fast, accurate and label‐free method for measuring
the thermodynamics and binding affinities of molecular associations in solution. Because the …

Recent progress in genetics, fed by the burst in genome sequence data, has led to the
identification of a host of novel bacterial heme proteins that are now being characterized in …

A global proteomic evaluation of the response of the marine bacterium Pseudomonas
fluorescens BA3SM1 to Cd, Zn and Cu was performed by two dimensional gel …

Enterococcus faecalis is a major opportunistic pathogen that readily forms protective biofilms
leading to chronic infections. Biofilms protect bacteria from detergent solutions, antimicrobial …

The human gut microbiota is able to degrade otherwise undigestible polysaccharides,
largely through the activity of Bacteroides. Uptake of polysaccharides into Bacteroides is …

The obligate intracellular pathogen Chlamydia trachomatis, along with its close species
relatives, is known to be strictly dependent upon the availability of iron. Deprivation of iron in …