Biotechnological, biomedical, and agronomical applications of plant protease inhibitors with high stability: A systematic review

J Cotabarren, D Lufrano, MG Parisi, WD Obregón - Plant Science, 2020 - Elsevier
Protease inhibitors (PIs) are regulatory proteins found in numerous animal tissues and
fluids, plants, and microorganisms that reduce and inhibit the exacerbated and uncontrolled …

[HTML][HTML] Black garlic improves heart function in patients with coronary heart disease by improving circulating antioxidant levels

J Liu, G Zhang, X Cong, C Wen - Frontiers in physiology, 2018 - frontiersin.org
Background: Black garlic (BG) has many health-promoting properties. Objectives: We aimed
to explore the clinical effects of BG on chronic heart failure (CHF) in patients with coronary …

Deciphering the binding of carbendazim (fungicide) with human serum albumin: A multi-spectroscopic and molecular modelling studies

MF Siddiqui, MS Khan, FM Husain… - Journal of Biomolecular …, 2019 - Taylor & Francis
Carbendazim is a benzimidazole fungicide used to control the fungal invasion. However, its
exposure might lead to potential health problems. The present study evaluates the …

ClCPI, a cysteine protease inhibitor purified from Cassia leiandra seeds has antifungal activity against Candida tropicalis by inducing disruption of the cell surface

IRS Melo, LP Dias, NMS Araújo, IM Vasconcelos… - International journal of …, 2019 - Elsevier
Infections caused by Candida tropicalis have increased significantly worldwide in parallel
with resistance to antifungal drugs. To overcome resistance novel drugs have to be …

[HTML][HTML] Purification and Characterization of a Novel Thermostable Papain Inhibitor from Moringa oleifera with Antimicrobial and Anticoagulant Properties

J Cotabarren, S Claver, JA Payrol, J Garcia-Pardo… - Pharmaceutics, 2021 - mdpi.com
Plant cystatins (or phytocystatins) comprise a large superfamily of natural bioactive small
proteins that typically act as protein inhibitors of papain-like cysteine proteases. In this …

Assessment of standardization of domestic commercial black garlic extract for S-allyl-l-cysteine and S-1-propenyl-l-cysteine

HJ Woo, GS Cha, MJ Kang, KH Kyung - Food Science and Biotechnology, 2022 - Springer
Aged garlic extract (AGE) contains a significant amount of bioactive compounds, including S-
allyl-l-cysteine (SAC), which is associated with various health benefits. Among different AGE …

[HTML][HTML] Biotechnological Potential of Araucaria angustifolia Pine Nuts Extract and the Cysteine Protease Inhibitor AaCI-2S

RC Sallai, BR Salu, RA Silva-Lucca, FL Alves… - Plants, 2020 - mdpi.com
Protease inhibitors are involved in the regulation of endogenous cysteine proteases during
seed development and play a defensive role because of their ability to inhibit exogenous …

Insight into the biochemical characterization of phytocystatin from Glycine max and its interaction with Cd+2 and Ni+2

S Siddiqui, MF Siddiqui, S Khan… - Journal of Molecular …, 2019 - Wiley Online Library
Phytocystatins are cysteine proteinase inhibitors ubiquitously present in plants and animals.
They are known to carry out various significant physiological functions and also maintain the …

Probing the binding effects of zinc and cadmium with garlic phytocystatin: Implication of the abiotic stress on garlic phytocystatin

MF Siddiqui, B Bano - International journal of biological macromolecules, 2019 - Elsevier
Abiotic stress induced by heavy metals retards the growth and development of plants.
Therefore, it is essential to have an insight into the potential toxic effects of heavy metals …

Purification and characterization of a cystatin like thiol protease inhibitor from Brassica nigra

A Feroz, PSS Khaki, AA Siddiqui, F Amin… - International journal of …, 2019 - Elsevier
Phytocystatins or plant cystatins belong to a group of thiol protease inhibitors present
ubiquitously in living system. They play a crucial role in cellular protein turnover thereby …