The role of CSTF2 in cancer: from technology to clinical application

J Ding, Y Su, Y Liu, Y Xu, D Yang, X Wang, S Hao… - Cell Cycle, 2023 - Taylor & Francis
ABSTRACT A protein called cleavage-stimulating factor subunit 2 (CSTF2, additionally
called CSTF-64) binds RNA and is needed for the cleavage and polyadenylation of mRNA …

Human CSTF2 RNA Recognition Motif Domain Binds to a U-Rich RNA Sequence through a Multistep Binding Process

E Masoumzadeh, MP Latham - Biochemistry, 2024 - ACS Publications
The RNA recognition motif (RRM) is a conserved and ubiquitous RNA-binding domain that
plays essential roles in mRNA splicing, polyadenylation, transport, and stability. RRM …