The poor transferability of genetic risk scores (GRSs) derived from European ancestry data
in diverse populations is a cause of concern. We set out to evaluate whether GRSs derived …

Summary LDL-C PRS help explain part of hypercholesterolemia in a proportion of
dyslipidemic patients that do not have monogenic FH. Nevertheless, the CVD risk conferred …

Most genome-wide association studies are based on samples of European descent. We
assess whether the genetic determinants of blood lipids, a major cardiovascular risk factor …

Polygenic scores for dyslipidemia: the emerging genomic mode... : Current Opinion in Lipidology
Polygenic scores for dyslipidemia: the emerging genomic model of plasma lipoprotein trait …

New data on lipid and fatty acid profiles are presented, and the dynamics of the studied
components in muscles in the males and females of the beaked redfish, Sebastes mentella …

Background Dyslipidemias, including familial hypercholesterolemia (FH), are a significant
risk factor for cardiovascular diseases. FH is a genetic disorder resulting in elevated levels of …

The occurrence of dyslipidaemia, which is an established risk factor for cardiovascular
diseases, has been attributed to multiple factors including genetic and environmental …

Abstract Polygenic Risk Score (PRS) analysis is a method that predicts the genetic risk of an
individual towards targeted traits. Even when there are no significant markers, it gives …

Lumbar disc degeneration (LDD) is age-related break-down in the fibrocartilaginous joints
between lumbar vertebrae. It is a major cause of low back pain and is conventionally …

Polygenic risk scores (PRS) based on genome-wide discoveries are promising predictors or
classifiers of disease development, severity, and/or progression for common clinical …