Hypoxia signaling in human health and diseases: implications and prospects for therapeutics

Z Luo, M Tian, G Yang, Q Tan, Y Chen, G Li… - Signal transduction and …, 2022 - nature.com
Molecular oxygen (O2) is essential for most biological reactions in mammalian cells. When
the intracellular oxygen content decreases, it is called hypoxia. The process of hypoxia is …

[HTML][HTML] Plant-derived bioactive compounds in colon cancer treatment: An updated review

A Esmeeta, S Adhikary, V Dharshnaa… - Biomedicine & …, 2022 - Elsevier
Colon cancer is the third most predominant cancer caused by genetic, environmental and
nutritional factors. Plant-based compounds are very well known to regress colon cancer in …

[PDF][PDF] Estimations nationales de l'incidence et de la mortalité par cancer en France métropolitaine entre 1990 et 2018

G Defossez, S Le Guyader-Peyrou, Z Uhry… - Étude à partir des …, 2019 - researchgate.net
Le plan cancer 2014‑2019, qui entre dans sa dernière année, s' in‑titule «Guérir et prévenir
les cancers: donnons les mêmes chances à tous, partout en France». Il met d'emblée la …

Evaluating intrinsic and non-intrinsic cancer risk factors

S Wu, W Zhu, P Thompson, YA Hannun - Nature communications, 2018 - nature.com
Discriminating the contribution of unmodifiable random intrinsic DNA replication errors ('bad
luck') to cancer development from those of other factors is critical for understanding cancer in …

Colorectal cancer screening: a global overview of existing programmes

EH Schreuders, A Ruco, L Rabeneck, RE Schoen… - Gut, 2015 - gut.bmj.com
Colorectal cancer (CRC) ranks third among the most commonly diagnosed cancers
worldwide, with wide geographical variation in incidence and mortality across the world …

[HTML][HTML] Prevalence and risk factors of colorectal cancer in Asia

MCS Wong, H Ding, J Wang, PSF Chan… - Intestinal …, 2019 - synapse.koreamed.org
Globally, colorectal cancer (CRC) is a substantial public health burden, and it is increasingly
affecting populations in Asian countries. The overall prevalence of CRC is reported to be low …

Participation and yield of a population-based colorectal cancer screening programme in China

H Chen, N Li, J Ren, X Feng, Z Lyu, L Wei, X Li, L Guo… - Gut, 2019 - gut.bmj.com
Objective Colorectal cancer (CRC) screening has been widely implemented in many
countries. However, evidence on participation and diagnostic yield of population-based …

Obesity and risk of colorectal cancer: a systematic review of prospective studies

Y Ma, Y Yang, F Wang, P Zhang, C Shi, Y Zou, H Qin - PloS one, 2013 - journals.plos.org
Background Mounting evidence indicates that obesity may be associated with the risk of
colorectal cancer (CRC). To conduct a systematic review of prospective studies assessing …

Fecal bacteria act as novel biomarkers for noninvasive diagnosis of colorectal cancer

Q Liang, J Chiu, Y Chen, Y Huang, A Higashimori… - Clinical Cancer …, 2017 - AACR
Purpose: Gut microbiota have been implicated in the development of colorectal cancer. We
evaluated the utility of fecal bacterial marker candidates identified by our metagenome …

Edible ginger-derived nano-lipids loaded with doxorubicin as a novel drug-delivery approach for colon cancer therapy

M Zhang, B Xiao, H Wang, MK Han, Z Zhang… - Molecular Therapy, 2016 - cell.com
The use of nanotechnology for drug delivery has shown great promise for improving cancer
treatment. However, potential toxicity, hazardous environmental effects, issues with large …