Hormones, sex, and asthma

JA Yung, H Fuseini, DC Newcomb - Annals of Allergy, Asthma & …, 2018 - Elsevier
Objective To summarize the current literature on the sex disparity in asthma and the role of
sex hormone signaling in allergic and neutrophilic airway inflammation. Data Sources …

[HTML][HTML] Challenges of clustering multimodal clinical data: review of applications in asthma subtyping

E Horne, H Tibble, A Sheikh… - JMIR medical …, 2020 - medinform.jmir.org
Background: In the current era of personalized medicine, there is increasing interest in
understanding the heterogeneity in disease populations. Cluster analysis is a method …

[HTML][HTML] Characterization of asthma by age of onset: a multi-database cohort study

EJ Baan, EW de Roos, M Engelkes, M de Ridder… - The Journal of Allergy …, 2022 - Elsevier
Background Asthma can occur at any age but the differences in patient characteristics
between childhood-, adult-, and late-onset asthma are not well understood. Objective To …

[HTML][HTML] Asthma phenotyping in primary care: applying the International Severe Asthma Registry eosinophil phenotype algorithm across all asthma severities

M Kerkhof, TN Tran, R Allehebi, GW Canonica… - The Journal of Allergy …, 2021 - Elsevier
Background We developed an eosinophil phenotype gradient algorithm and applied it to a
large severe asthma cohort (International Severe Asthma Registry). Objective We sought to …

Data‐driven adult asthma phenotypes based on clinical characteristics are associated with asthma outcomes twenty years later

A Boudier, S Chanoine, S Accordini, JM Anto… - Allergy, 2019 - Wiley Online Library
Background Research based on cluster analyses led to the identification of particular
phenotypes confirming phenotypic heterogeneity of asthma. The long‐term clinical course of …

[HTML][HTML] Cigarette smoking and asthma

NC Thomson, R Polosa, DD Sin - The Journal of Allergy and Clinical …, 2022 - Elsevier
Globally, around half the adult asthma population are current or former cigarette smokers.
Cigarette smoking and asthma interact to induce an “asthma-smoking phenotype (s),” which …

Revisiting mild asthma: current knowledge and future needs

A Mohan, A Ludwig, C Brehm, NL Lugogo, K Sumino… - Chest, 2022 - Elsevier
Asthma is a common chronic airways disease with significant impact on patients, caregivers,
and the health care system. Although most research and novel interventions mainly have …

Data-driven questionnaire-based cluster analysis of asthma in Swedish adults

MA Kisiel, X Zhou, J Sundh, B Ställberg… - NPJ primary care …, 2020 - nature.com
The aim of this study was to identify asthma phenotypes through cluster analysis. Cluster
analysis was performed using self-reported characteristics from a cohort of 1291 Swedish …

A systematic review of asthma phenotypes derived by data-driven methods

F Cunha, R Amaral, T Jacinto, B Sousa-Pinto… - Diagnostics, 2021 - mdpi.com
Classification of asthma phenotypes has a potentially relevant impact on the clinical
management of the disease. Methods for statistical classification without a priori …

[HTML][HTML] Determining factors affecting nurses' acceptance of a care plan system using a modified technology acceptance model 3: structural equation model with cross …

KF Ho, PC Chang, MD Kurniasari… - JMIR medical …, 2020 - medinform.jmir.org
Background: Health information technology is used in nursing practice worldwide, and
holistic patient care planning can serve as a guide for nursing practice to ensure quality in …