A principle concern of pharmacovigilance is the timely detection of adverse drug reactions
that are novel by virtue of their clinical nature, severity and/or frequency. The cornerstone of …

Aims To discuss the potential use of data mining and knowledge discovery in databases for
detection of adverse drug events (ADE) in pharmacovigilance. Methods A literature search …

Background Inhibitors of dipeptidyl peptidase (DPP)‐IV have been suspected in the onset of
bullous pemphigoid for several years now. However, comparative studies assessing the link …

Remdesivir is approved for emergency use by the US Food and Drug Administration (FDA)
and authorized conditionally by the European Medicines Agency (EMA) for patients with …

Detection, verification, and quantification of adverse drug reactions | The BMJ Skip to main
content Intended for healthcare professionals Access provided by Google Indexer Subscribe …

In the last 5 years, regulatory agencies and drug monitoring centres have been developing
computerised data-mining methods to better identify reporting relationships in spontaneous …

Aims Acute kidney injury (AKI) is associated with a high hospitalization rate, accelerated
long‐term decline in kidney function and a high mortality rate. Adverse drug reactions …

Background: Cardiovascular safety concerns for major cardiovascular events (MACE) were
raised during the clinical trials of romosozumab. We aimed to evaluate the cardiovascular …

Objective This study aimed to evaluate the risk for hepatotoxicity with nimesulide, a non-
steroidal anti-inflammatory drug (NSAID) available in Republic of Korea but withdrawn from …

The primary aim of spontaneous reporting systems (SRSs) is the timely detection of
unknown adverse drug reactions (ADRs), or signal detection. Generally this is carried out by …