Plus-end-tracking proteins and their interactions at microtubule ends

N Galjart - Current Biology, 2010 - cell.com
Microtubules are cytoskeletal elements that are essential for a large number of intracellular
processes, including mitosis, cell differentiation and migration, and vesicle transport. In …

Microtubule-depolymerizing kinesins

CE Walczak, S Gayek, R Ohi - Annual review of cell and …, 2013 - annualreviews.org
The microtubule (MT) cytoskeleton supports a broad range of cellular functions, from
providing tracks for intracellular transport, to supporting movement of cilia and flagella, to …

Phase separation of EB1 guides microtubule plus-end dynamics

X Song, F Yang, T Yang, Y Wang, M Ding, L Li… - Nature Cell …, 2023 - nature.com
In eukaryotes, end-binding (EB) proteins serve as a hub for orchestrating microtubule
dynamics and are essential for cellular dynamics and organelle movements. EB proteins …

Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis

X Song, F Yang, X Liu, P Xia, W Yin, Z Wang… - Nature Chemical …, 2021 - nature.com
Spindle position control is essential for cell fate determination and organogenesis. Early
studies indicate the essential role of the evolutionarily conserved Gαi/LGN/NuMA network in …

Phase separation drives decision making in cell division

X Liu, X Liu, H Wang, Z Dou, K Ruan, DL Hill… - Journal of Biological …, 2020 - ASBMB
Liquid–liquid phase separation (LLPS) of biomolecules drives the formation of subcellular
compartments with distinct physicochemical properties. These compartments, free of lipid …

From signaling pathways to microtubule dynamics: the key players

S Etienne-Manneville - Current opinion in cell biology, 2010 - Elsevier
Microtubules are highly dynamic structures whose regulation is crucial for cell division, cell
polarity, cell migration, or neuronal differentiation. Because they contribute to most cellular …

Regulation of end-binding protein EB1 in the control of microtubule dynamics

A Nehlig, A Molina, S Rodrigues-Ferreira… - Cellular and Molecular …, 2017 - Springer
The regulation of microtubule dynamics is critical to ensure essential cell functions, such as
proper segregation of chromosomes during mitosis or cell polarity and migration. End …

[HTML][HTML] Hericium erinaceus, a medicinal fungus with a centuries-old history: evidence in gastrointestinal diseases

AG Gravina, R Pellegrino, S Auletta… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Hericium erinaceus is an edible and medicinal mushroom commonly used in traditional
Chinese medicine for centuries. Several studies have highlighted its therapeutic potential for …

Kinesin-13s in mitosis: Key players in the spatial and temporal organization of spindle microtubules

SC Ems-McClung, CE Walczak - Seminars in cell & developmental biology, 2010 - Elsevier
Dynamic microtubules are essential for the process of mitosis. Thus, elucidating when,
where, and how microtubule dynamics are regulated is key to understanding this process …

+ TIPs: SxIPping along microtubule ends

P Kumar, T Wittmann - Trends in cell biology, 2012 - cell.com
+ TIPs are a heterogeneous class of proteins that specifically bind to growing microtubule
ends. Because dynamic microtubules are essential for many intracellular processes,+ TIPs …