Patients with severe chronic graft-versus-host disease (cGVHD) always experience
debilitating tissue injury and have poorer quality of life and shorter survival time. The early …

Chronic kidney disease (CKD) is one of the most common complications of diabetes mellitus
and an independent risk factor for cardiovascular disease. Despite guideline-directed …

The renin-angiotensin-aldosterone system is a neurohormonal system responsible for
maintaining homeostasis of fluid regulation, sodium balance, and blood pressure. The …

Diabetes-associated complications are a major global health concern. In diabetics, the
increased accumulation of sorbitol, produced via over activated polyol pathway, from …

The imbalance between T helper 17 (Th17) and regulatory T (Treg) cells is an important
mechanism in the pathogenesis of diabetic nephropathy (DN). Serum/glucocorticoid …

IFNγ-secreting T cells are central for the maintenance of immune surveillance within the
central nervous system (CNS). It was previously reported in healthy donors that the T-cell …

Arid environments continue to increase their global coverage yearly due to climate change,
and leaves harsh environmental effects in their wake. Of these effects—which include high …

T cells are involved in immune surveillance of the central nervous system (CNS) in
recognizing microbial infections as blocking T-cell traffic to the CNS that can result in viral …

Background: Diabetic nephropathy (DN) is a serious complication of diabetes with rising
prevalence worldwide. We aimed to explore the anti-DN mechanisms of the compound …

Background: Diabetic nephropathy (hereinafter referred to as DN) is one of the important
causes of chronic renal failure, with great harm. We aimed to elucidate the role of transgelin …