Scientists had long wondered whether there existed" subsets" of CD4+ T cells that could
mediate specific responses. This concept was validated by the seminal discovery by …

Naturally‐occurring regulatory T cells (Tregs) are emerging as key regulators of immune
responses to self‐tissues and infectious agents. Insight has been gained into the cell types …

Many pathological processes, including those causing allergies and autoimmune diseases,
are associated with the presence of specialized subsets of T helper cells (TH1 and TH2) at …

An important function of the sympathetic nervous system is to maintain homeostasis by
modulating the level of cellular activity in many diverse organ systems. The sympathetic …

Marijuana and many of its constituent cannabinoids influence the central nervous system
(CNS), probably through the cannabinoid receptor, which has recently been cloned in rat …

During human immunodeficiency virus infection and allergic diseases, characterized by a
dominant T helper (Th) 2 response, overproduction of prostaglandin E2 (PGE2) is observed …

Prostaglandins, particularly those of the E series, are widely regarded as
immunosuppressive products of eukaryotic cells that can downregulate many aspects of B …

Primary and secondary lymphoid organs are innervated extensively by noradrenergic
sympathetic nerve fibers. Lymphocytes, macrophages, and other cells of the immune system …

PGE2 is a well known immunomodulator that has multiple effects on the immune system. We
demonstrate that PGE2 selectively and dose dependently inhibits IL-2 and IFN-gamma …

Objective: To analyze temporal artery specimens from patients with giant cell arteritis and
polymyalgia rheumatica for the presence of inflammatory cytokines and to ascertain whether …