Bone sarcomas are rare heterogeneous tumors that affect patients of all ages including
children, adolescent young adults, and older adults. They include many aggressive …

Purpose: To analyze the risk and benefit of high-dose chemotherapy followed by stem cell
transplantation (HDCT-SCT) treatment in patients with advanced retinoblastoma. Design …

Background Ewing sarcoma (ES) represents the second most common malignant bone
tumor in children and young adults. ES is not a frequent finding in sites different from the …

Melatonin is a hormone secreted mainly by the pineal gland and acts through the Mel1A and
Mel1B receptors. Among other actions, melatonin significantly increases osteogenesis …

Background outcome of primary refractory or recurrent Ewing sarcoma (RRES) is poor and
the role of high-dose therapy (HDT) remains uncertain. We retrospectively reviewed all …

Ewing sarcoma (ES) is a malignant tumor of bone and soft tissue that most often occurs in
adolescents and young adults. Despite an international coordinated approach, several …

The goal of the research was to investigate if a combination of vincristine, irinotecan and
temozolomide (VIT) could benefit adult patients with metastatic Ewing sarcoma who had …

Background Ewing sarcomas are solid tumours of the bone and soft tissue, that usually
affect children, adolescents, and young adults. The incidence is about three cases per …

Forty-seven patients with metastatic disease at diagnosis or recurrent Ewing sarcoma (EWS)
received high-dose chemotherapy (HDC) followed by tandem (n= 20, from February 13 …

Background Ewing family of tumors (EFT) is rarely diagnosed in patients (pts) over the age
of 18 years (years), and data on the clinical course and the outcome of adult EFT pts is …