Selection of boron reagents for Suzuki–Miyaura coupling

AJJ Lennox, GC Lloyd-Jones - Chemical Society Reviews, 2014 - pubs.rsc.org
Suzuki–Miyaura (SM) cross-coupling is arguably the most widely-applied transition metal
catalysed carbon–carbon bond forming reaction to date. Its success originates from a …

Asymmetric synthesis of secondary and tertiary boronic esters

BSL Collins, CM Wilson, EL Myers… - Angewandte Chemie …, 2017 - Wiley Online Library
Non‐racemic chiral boronic esters are recognised as immensely valuable building blocks in
modern organic synthesis. Their stereospecific transformation into a variety of functional …

Amphotericin primarily kills yeast by simply binding ergosterol

KC Gray, DS Palacios, I Dailey… - Proceedings of the …, 2012 - National Acad Sciences
Amphotericin B (AmB) is a prototypical small molecule natural product that can form ion
channels in living eukaryotic cells and has remained refractory to microbial resistance …

Alkenyl boronates: synthesis and applications

J Carreras, A Caballero… - Chemistry–An Asian …, 2019 - Wiley Online Library
Organoboron compounds have become one of the most versatile building blocks in organic
synthesis owing to their accessible and efficient conversion into many different functional …

Stereospecific couplings of secondary and tertiary boronic esters

D Leonori, VK Aggarwal - Angewandte Chemie International …, 2015 - Wiley Online Library
This Minireview highlights advances in the Suzuki–Miyaura cross‐coupling of secondary
boron reagents for the creation of C C bonds with control of stereochemistry. It also …

The molecular industrial revolution: automated synthesis of small molecules

M Trobe, MD Burke - Angewandte Chemie International Edition, 2018 - Wiley Online Library
Today we are poised for a transition from the highly customized crafting of specific molecular
targets by hand to the increasingly general and automated assembly of different types of …

Enantiospecific and iterative Suzuki–Miyaura cross-couplings

JPG Rygus, CM Crudden - Journal of the American Chemical …, 2017 - ACS Publications
The Suzuki–Miyaura cross-coupling reaction has emerged as one of the most powerful
methods for the construction of carbon–carbon bonds. Though most widely utilized for the …

Ir‐Catalyzed Enantioselective Synthesis of gem‐Diborylalkenes Enabled by 1,2‐Boron Shift

JF Ge, XZ Zou, XR Liu, CL Ji, XY Zhu… - Angewandte Chemie …, 2023 - Wiley Online Library
Asymmetric cross‐couplings based on 1, 2‐carbon migration from B‐ate complexes have
been developed efficiently to access valuable organoboronates. However, enantioselective …

Asymmetric synthesis of α-aminoboronic acid derivatives by copper-catalyzed enantioselective hydroamination

D Nishikawa, K Hirano, M Miura - Journal of the American …, 2015 - ACS Publications
A copper-catalyzed regio-and enantioselective hydroamination of alkenyl dan boronates
(dan= 1, 8-diaminonaphthyl) with hydrosilanes and hydroxylamines proceeds to deliver the …

Mechanism and scope of nickel-catalyzed decarbonylative borylation of carboxylic acid fluorides

CA Malapit, JR Bour, SR Laursen… - Journal of the American …, 2019 - ACS Publications
This Article describes the development of a base-free, nickel-catalyzed decarbonylative
coupling of carboxylic acid fluorides with diboron reagents to selectively afford aryl boronate …