New insights into the role of neuron-specific enolase in neuro-inflammation, neurodegeneration, and neuroprotection

A Haque, R Polcyn, D Matzelle, NL Banik - Brain sciences, 2018 - mdpi.com
Neurodegeneration is a complex process that leads to irreversible neuronal damage and
death in spinal cord injury (SCI) and various neurodegenerative diseases, which are …

[HTML][HTML] Stress and brain immunity: Microglial homeostasis through hypothalamus-pituitary-adrenal gland axis and sympathetic nervous system

S Sugama, Y Kakinuma - Brain, Behavior, & Immunity-Health, 2020 - Elsevier
Stress has been well documented to bring about various clinical disorders, ranging from
neurodegeneration, such as Parkinson's (PD) and Alzheimer's diseases (AD), to metabolic …

Microglia and HPA axis in depression: An overview of participation and relationship

G Cheiran Pereira, E Piton… - The World Journal of …, 2022 - Taylor & Francis
Objectives: This narrative review article provides an overview on the involvement of
microglia and the hypothalamic-pituitary-adrenal (HPA) axis in the pathophysiology of …

Bidirectional communication between mast cells and the gut-brain axis in neurodegenerative diseases: avenues for therapeutic intervention

P Bhuiyan, Y Chen, M Karim, H Dong, Y Qian - Brain research bulletin, 2021 - Elsevier
Although the global incidence of neurodegenerative diseases has been steadily increasing,
especially in adults, there are no effective therapeutic interventions. Neurodegeneration is a …

Bidirectional relationship of mast cells-neurovascular unit communication in neuroinflammation and its involvement in POCD

N Li, X Zhang, H Dong, Y Hu, Y Qian - Behavioural Brain Research, 2017 - Elsevier
Postoperative cognitive dysfunction (POCD) has been hypothesized to be mediated by
surgery-induced neuroinflammation, which is also a key element in the pathobiology of …

[HTML][HTML] Therapeutic effect of acute and chronic use of different doses of vitamin D3 on seizure responses and cognitive impairments induced by pentylenetetrazole in …

H Jiang, S Zhang - Iranian Journal of Basic Medical Sciences, 2022 - ncbi.nlm.nih.gov
Objective (s): This study aimed to evaluate the effects of acute and chronic intake of different
doses of vitamin D3 on seizure responses and cognitive impairment induced by …

Oxidative stress induced by the anti-cancer agents, plumbagin, and atovaquone, inhibits ion transport through Na+/K+-ATPase

Y Alharbi, A Kapur, M Felder, L Barroilhet… - Scientific Reports, 2020 - nature.com
Oxidative stress inhibits Na+/K+-ATPase (NKA), the ion channel that maintains membrane
potential. Here, we investigate the role of oxidative stress-mediated by plumbagin and …

Functional differentiation in the transverse plane of the hippocampus: An update on activity segregation within the DG and CA3 subfields

MAA Meyer, J Radulovic - Brain research bulletin, 2021 - Elsevier
Decades of neuroscience research in rodents have established an essential role of the
hippocampus in the processing of episodic memories. Based on accumulating evidence of …

Concurrent Brain Subregion Microgliosis in an HLA-II Mouse Model of Group A Streptococcal Skin Infection

S Nookala, S Mukundan, B Grove, C Combs - Microorganisms, 2023 - mdpi.com
The broad range of clinical manifestations and life-threatening infections caused by the
Gram-positive bacterium, Streptococcus pyogenes or Group A Streptococcus (GAS) …

Corticosterone and progesterone differentially regulate HPA axis and neuroimmune responses to stress in male rats

CM Hueston, T Deak - Stress, 2020 - Taylor & Francis
In response to stressor exposure, expression of the inflammatory cytokine interleukin-1β (IL-
1) is increased within the paraventricular nucleus of the hypothalamus (PVN). Surgical …