Host parasite interactions and pathophysiology in Giardia infections

JA Cotton, JK Beatty, AG Buret - International journal for parasitology, 2011 - Elsevier
Giardia is a protozoan parasite of the small intestine, and a leading cause of diarrhoeal
disease worldwide in a variety of animals, including humans. The host–parasite interaction …

Mechanisms of epithelial dysfunction in giardiasis

AG Buret - Gut, 2007 - gut.bmj.com
Infection with the ubiquitous intestinal parasite Giardia lamblia (synonymous G duodenalis
or G intestinalis) may cause acute or chronic diarrhoea, dehydration, abdominal discomfort …

Characterization of the Giardia intestinalis secretome during interaction with human intestinal epithelial cells: The impact on host cells

SY Ma'ayeh, J Liu, D Peirasmaki… - PLoS neglected …, 2017 - journals.plos.org
Background Giardia intestinalis is a non-invasive protozoan parasite that causes giardiasis
in humans, the most common form of parasite-induced diarrhea. Disease mechanisms are …

Release of metabolic enzymes by Giardia in response to interaction with intestinal epithelial cells

E Ringqvist, JED Palm, H Skarin, AB Hehl… - Molecular and …, 2008 - Elsevier
Giardia lamblia, an important cause of diarrheal disease, resides in the small intestinal
lumen in close apposition to epithelial cells. Since the disease mechanisms underlying …

Microvesicles released from Giardia intestinalis disturb host-pathogen response in vitro

I Evans-Osses, A Mojoli, M Monguió-Tortajada… - European journal of cell …, 2017 - Elsevier
Giardia intestinalis (GI), is an anaerobic protozoan and the aetiological agent of giardiasis, a
diarrhoea present worldwide and associated with poverty. GI has a simple life cycle …

Systemic and Mucosal Responses to Oral Administration of Excretory and Secretory Antigens from Giardia intestinalis

JC Jiménez, J Fontaine, JM Grzych… - Clinical and Vaccine …, 2004 - Am Soc Microbiol
Giardia, a flagellated protozoan that infects the upper small intestine of its vertebrate host, is
the most common parasitic protist responsible for diarrhea worldwide. Molecules released …

Giardia duodenalis-induced alterations of commensal bacteria kill Caenorhabditis elegans: a new model to study microbial-microbial interactions in the gut

TK Gerbaba, P Gupta, K Rioux… - American Journal of …, 2015 - journals.physiology.org
Giardia duodenalis is the most common cause of parasitic diarrhea worldwide and a well-
established risk factor for postinfectious irritable bowel syndrome. We hypothesized that …

Transcriptional changes in Giardia during host–parasite interactions

E Ringqvist, L Avesson, F Söderbom… - International journal for …, 2011 - Elsevier
Giardia intestinalis is one of the major causes of parasite-induced diarrhea. The disease,
giardiasis, is caused by trophozoites attaching to the intestinal epithelium, resulting in …

Giardia duodenalisAssemblage-Specific Induction of Apoptosis and Tight Junction Disruption in Human Intestinal Epithelial Cells: Effects of Mixed Infections

WH Koh, T Geurden, T Paget… - The Journal of …, 2013 - meridian.allenpress.com
In view of the interest in genotype-specific pathogenesis in Giardia duodenalis, the aim of
the present study was to examine the effects of infection with different, or mixed, G …

Giardia duodenalis Induces Apoptosis in Intestinal Epithelial Cells via Reactive Oxygen Species-Mediated Mitochondrial Pathway In Vitro

L Liu, R Fang, Z Wei, J Wu, X Li, W Li - Pathogens, 2020 - mdpi.com
The intestinal protozoan parasite, Giardia duodenalis, infects a large number of people in
the world annually. Giardia infection has been considered a negative effect on intestinal …