Plight of CORMs: The unreliability of four commercially available CO-releasing molecules, CORM-2, CORM-3, CORM-A1, and CORM-401, in studying CO biology
Carbon monoxide (CO) is an endogenously produced gaseous signaling molecule with
demonstrated pharmacological effects. In studying CO biology, three delivery forms have …
demonstrated pharmacological effects. In studying CO biology, three delivery forms have …
A topological switch in CFTR modulates channel activity and sensitivity to unfolding
The cystic fibrosis transmembrane conductance regulator (CFTR) anion channel is essential
to maintain fluid homeostasis in key organs. Functional impairment of CFTR due to …
to maintain fluid homeostasis in key organs. Functional impairment of CFTR due to …
Crucial role of carbon monoxide as a regulator of diarrhea caused by cholera toxin: Evidence of direct interaction with toxin
LD da Silva, JLS Pinheiro, LHM Rodrigues… - Biochemical …, 2023 - Elsevier
The present study evaluated the role of heme oxygenase 1 (HO-1)/carbon monoxide (CO)
pathway in the cholera toxin-induced diarrhea and its possible action mechanism. The …
pathway in the cholera toxin-induced diarrhea and its possible action mechanism. The …
[PDF][PDF] Utilisation of CFTR orthologues to evaluate new therapies for cystic fibrosis
D Ng - 2022 - research-information.bris.ac.uk
Large animal models are valuable to investigate the pathophysiology of the genetic disease
cystic fibrosis (CF) and test new therapies. Due to species-specific differences in the function …
cystic fibrosis (CF) and test new therapies. Due to species-specific differences in the function …