Kidney diseases are major health problem and understanding the underlined mechanisms
that lead to kidney diseases are critical research points with a marked potential impact on …

There is a vital link between human and nature since it contains several essential elements
to his well-being and this in all areas. Indeed, whether for food, health or pharmaceutical …

During aging, the production of androgens by the testis Leydig cells gradually decreases.
Phenolic compounds can improve testosterone biosynthesis and delay the onset of …

Avenanthramides (AVAs) present in oats are amides of anthranilic and cinnamic acids.
AVAs are potent antioxidants and have anti-inflammatory properties. There are various …

Caffeic acid phenethyl ester (CAPE, 2), a natural compound from propolis, is a well-
documented antitumor agent with nuclear factor kappa B (NF-κB) inhibitory activity. Key …

The inflammatory response is an essential process for the host defence against pathogens.
Lipid mediators are important in coordinating the pro-inflammatory and pro-resolution …

Abstract The inhibition of 5-lipoxygenase (5-LO), the key enzyme for the biosynthesis of
leukotrienes (LTs), has generated increasing enthusiasm as anti-inflammatory and antitumor …

Sinapic acid is found in many edible plants and fruits, such as rapeseed, where it is the
predominant phenolic compound. New sinapic acid phenethyl ester (SAPE) analogues were …

lipoxygenase (5‐LO) catalyzes the biosynthesis of leukotrienes, potent lipid mediators
involved in inflammatory diseases, and both 5‐LO and the leukotrienes are validated …

A novel series of zileuton-hydroxycinnamic acid hybrids were synthesized and screened as
5-lipoxygenase (5-LO) inhibitors in stimulated HEK293 cells and polymorphonuclear …