The role of metagenomics and next-generation sequencing in infectious disease diagnosis

S Miller, C Chiu - Clinical chemistry, 2022 - academic.oup.com
Background Metagenomic next-generation sequencing (mNGS) for pathogen detection is
becoming increasingly available as a method to identify pathogens in cases of suspected …

Bioinformatics tools used for whole-genome sequencing analysis of Neisseria gonorrhoeae: a literature review

R Singh, A Kusalik, JAR Dillon - Briefings in Functional …, 2022 - academic.oup.com
Whole-genome sequencing (WGS) data are well established for the investigation of
gonococcal transmission, antimicrobial resistance prediction, population structure …

Use of metagenomic next-generation sequencing to identify pathogens in pediatric osteoarticular infections

N Ramchandar, J Burns, NG Coufal… - Open forum …, 2021 - academic.oup.com
Abstract Background Osteoarticular infections (OAIs) are frequently encountered in children.
Treatment may be guided by isolation of a pathogen; however, operative cultures are often …

Qualitative and quantitative detection of multiple sexually transmitted infection pathogens reveals distinct associations with cervicitis and vaginitis

WT Kang, H Xu, Y Liao, Q Guo, Q Huang… - Microbiology …, 2022 - Am Soc Microbiol
Many diverse pathogens have been discovered from reproductive-tract infections, but the
relationship between the presence and abundance of particular pathogen species and …

Pediatric osteoarticular infections caused by Mycobacteria tuberculosis complex: a 26-year review of cases in San Diego, CA

I Drobish, N Ramchandar, V Raabe… - The Pediatric …, 2022 - journals.lww.com
Background: Osteoarticular infections (OAIs) account for 10%–20% of extrapulmonary
Mycobacteria tuberculosis (MTB) complex infections in children and 1%–2% of all pediatric …

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N Ramchandar, J Burns, NG Coufal, A Pennock… - 2021 - scholar.archive.org
Accepted Manuscript Page 1 Accepted Manuscript © The Author(s) 2021. Published by
Oxford University Press on behalf of Infectious Diseases Society of America. This is an …