[HTML][HTML] Triple-negative breast cancer: a review of conventional and advanced therapeutic strategies

MA Medina, G Oza, A Sharma, LG Arriaga… - International journal of …, 2020 - mdpi.com
Triple-negative breast cancer (TNBC) cells are deficient in estrogen, progesterone and
ERBB2 receptor expression, presenting a particularly challenging therapeutic target due to …

[HTML][HTML] Metastatic breast cancer: the potential of miRNA for diagnosis and treatment monitoring

A McGuire, JAL Brown, MJ Kerin - Cancer and metastasis reviews, 2015 - Springer
Breast cancer affects approximately 12% women worldwide and results in 14% of all cancer-
related fatalities. Breast cancer is commonly categorized into one of four main subtypes …

[HTML][HTML] MiRNA and LncRNA as potential biomarkers in triple-negative breast cancer: a review

SR Volovat, C Volovat, I Hordila, DA Hordila… - Frontiers in …, 2020 - frontiersin.org
Noncoding RNAs (ncRNAs) include a diverse range of RNA species, including microRNAs
(miRNAs) and long noncoding RNAs (lncRNAs). MiRNAs, ncRNAs of approximately 19–25 …

[HTML][HTML] miR-134 in extracellular vesicles reduces triple-negative breast cancer aggression and increases drug sensitivity

K O'Brien, MC Lowry, C Corcoran, VG Martinez… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Exosomes (EVs) have relevance in cell-to-cell communication carrying pro-tumorigenic
factors that participate in oncogenesis and drug resistance and are proposed to have …

[HTML][HTML] Triple negative breast cancer: the kiss of death

AA Jitariu, AM Cîmpean, D Ribatti, M Raica - Oncotarget, 2017 - ncbi.nlm.nih.gov
One of the most controversial women malignancies, triple negative breast cancers (TNBCs)
are critically overviewed here, being focused on data useful in clinical practice or to improve …

[HTML][HTML] MicroRNAs involved in carcinogenesis, prognosis, therapeutic resistance, and applications in human triple-negative breast cancer

L Ding, H Gu, X Xiong, H Ao, J Cao, W Lin, M Yu, J Lin… - Cells, 2019 - mdpi.com
Triple-negative breast cancer (TNBC) is the most aggressive, prevalent, and distinct subtype
of breast cancer characterized by high recurrence rates and poor clinical prognosis, devoid …

Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation

P Gasparini, F Lovat, M Fassan… - Proceedings of the …, 2014 - National Acad Sciences
Cell survival after DNA damage relies on DNA repair, the abrogation of which causes
genomic instability and development of cancer. However, defective DNA repair in cancer …

[HTML][HTML] Circulating cell-free miRNAs as biomarker for triple-negative breast cancer

VY Shin, JM Siu, I Cheuk, EKO Ng, A Kwong - British journal of cancer, 2015 - nature.com
Background: Triple-negative breast cancer (TNBC) accounts for 15–20% of all breast cancer
in women globally. This subtype often has early and high recurrence rates resulting in poor …

[HTML][HTML] A nineteen gene-based risk score classifier predicts prognosis of colorectal cancer patients

SK Kim, SY Kim, JH Kim, SA Roh, DH Cho, YS Kim… - Molecular …, 2014 - Elsevier
Colorectal cancer (CRC) patients frequently experience disease recurrence and distant
metastasis. This study aimed to identify prognostic indicators, including individual responses …

Role of androgen and microRNA in triple-negative breast cancer

N Al-Othman, M Ahram, M Alqaraleh - Breast disease, 2020 - content.iospress.com
Breast cancer (BC) is the most frequent type of malignancy affecting females worldwide.
Molecular–based studies resulted in an identification of at least four subtypes of breast …