Neurodegenerative diseases are pathologies of the central and peripheral nervous systems
characterized by loss of brain functions and problems in movement which occur due to the …

The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE)
syntaxin 5 (Stx5) in mammals and its ortholog Sed5p in Saccharomyces cerevisiae mediate …

Alzheimer's disease (AD) is a complex, multifactorial disease involving many pathological
mechanisms. Nonetheless, single pathogenic mutations in amyloid precursor protein (APP) …

Amyloid-β (Aβ) is a dynamic peptide of Alzheimer's disease (AD) which accelerates the
disease progression. At the cell membrane and cell compartments, the amyloid precursor …

Aims Although previous studies elaborated that selective autophagy was involved in quality
control of some organelles, including nucleus, mitochondria, the endoplasmic reticulum and …

The Golgi apparatus plays a crucial role in mediating the modification, transport, and sorting
of intracellular proteins and lipids. The morphological changes occurring in the Golgi …

The involvement of secretory pathways and Golgi dysfunction in neuronal cells during
Alzheimer's disease progression is poorly understood. Our previous overexpression and …

Membrane fusion, essential for a variety of biological processes, is ubiquitous and critical in
all living organisms. The soluble N-ethylmaleimide-sensitive factor attachment protein …

The Golgi apparatus is an intracellular organelle that modifies cargo, which is transported
extracellularly through the nucleus, endoplasmic reticulum, and plasma membrane in order …

Glutathione S-transferase (GST) genes play a protective role against oxidative stress and
may influence disease risk and drug pharmacokinetics. In this study, massive multiscalar …