In the past two decades, major breakthroughs that improve our understanding of the
pathophysiology and therapy of kidney stones (KS) have been lacking. The disease …

Nephrolithiasis is a common medical condition influenced by multiple environmental factors,
including diet. Since nutritional habits play a relevant role in the genesis and recurrence of …

The overall prevalence of kidney stones (KS) in the US rose from 3.2% in 1980 to 10.1% in
2016, but the trends in important subgroups have not been reported. We examined the …

Objective To evaluate trends in the incidence of kidney stones and characteristics
associated with changes in the incidence rate over 3 decades. Patients and Methods Adult …

Importance Type 2 diabetes (T2D) is associated with an increased risk of kidney stones.
Sodium-glucose cotransporter 2 inhibitors (SGLT2is) might lower the risk of nephrolithiasis …

Background Dietary and lifestyle factors may play an important role in the increasing
prevalence of nephrolithiasis. We aimed to review and quantify the associations between …

Objective To compare dietary factors between incident symptomatic stone formers and
controls, and among the incident stone formers, to determine whether dietary factors were …

Despite advances in the surgical management of urinary stone disease that have
significantly reduced patient morbidity, new stone formation and recurrence remain …

Background The relationship between the composition and function of gut microbial
communities and early-onset calcium oxalate kidney stone disease is unknown. Methods …

Results Among 3023 coded stone formers from 2000 to 2011, a total of 1515 were validated
and matched to 1515 controls (mean age was 45 years old, and 56% were men). After …