Host-and microbiota-derived extracellular vesicles, immune function, and disease development

L Macia, R Nanan, E Hosseini-Beheshti… - International journal of …, 2019 - mdpi.com
Extracellular vesicles (EVs) are blebs of either plasma membrane or intracellular
membranes carrying a cargo of proteins, nucleic acids, and lipids. EVs are produced by …

Cytokines and chemokines in cerebral malaria pathogenesis

J Dunst, F Kamena, K Matuschewski - Frontiers in cellular and …, 2017 - frontiersin.org
Cerebral malaria is among the major causes of malaria-associated mortality and effective
adjunctive therapeutic strategies are currently lacking. Central pathophysiological processes …

Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1‐based vaccines to prevent it

AR Jensen, Y Adams, L Hviid - Immunological reviews, 2020 - Wiley Online Library
Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …

Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells

CCY Li, SA Eaton, PE Young, M Lee, R Shuttleworth… - RNA biology, 2013 - Taylor & Francis
Interactions between glioma cells and their local environment are critical determinants of
brain tumor growth, infiltration and neovascularisation. Communication with host cells and …

Circulating microparticles: square the circle

NS Barteneva, E Fasler-Kan, M Bernimoulin, JNH Stern… - BMC cell biology, 2013 - Springer
Background The present review summarizes current knowledge about microparticles (MPs)
and provides a systematic overview of last 20 years of research on circulating MPs, with …

Blood–brain barrier in cerebral malaria: pathogenesis and therapeutic intervention

G Nishanth, D Schlüter - Trends in parasitology, 2019 - cell.com
Cerebral malaria is a life-threatening complication of malaria caused by the parasite
Plasmodium falciparum. The growing problem of drug resistance and the dearth of new …

Cerebral malaria: mysteries at the blood-brain barrier

L Rénia, SW Howland, C Claser, AC Gruner… - Virulence, 2012 - Taylor & Francis
Cerebral malaria is the most severe pathology caused by the malaria parasite, Plasmodium
falciparum. The pathogenic mechanisms leading to cerebral malaria are still poorly defined …

Microparticles and their emerging role in cancer multidrug resistance

J Gong, R Jaiswal, JM Mathys, V Combes… - Cancer treatment …, 2012 - Elsevier
Drug resistance is a major obstacle to the successful treatment of cancer as tumor cells
either fail to reduce in size following chemotherapy or the cancer recurs after an initial …

Cerebral Malaria and Neuronal Implications of Plasmodium Falciparum Infection: From Mechanisms to Advanced Models

OB Akide Ndunge, N Kilian, MM Salman - Advanced Science, 2022 - Wiley Online Library
Reorganization of host red blood cells by the malaria parasite Plasmodium falciparum
enables their sequestration via attachment to the microvasculature. This artificially increases …

Extracellular vesicles in malaria: an agglomeration of two decades of research

T Opadokun, P Rohrbach - Malaria Journal, 2021 - Springer
Malaria is a complex parasitic disease, caused by Plasmodium spp. More than a century
after the discovery of malaria parasites, this disease continues to pose a global public health …