Introduction The causal association between modifiable risk factors and erectile dysfunction
(ED) remains unclear, which hinders the early identification and intervention of patients with …

The meaning of sleep has puzzled people for millennia. In modern society, short sleep
duration is becoming a global problem. It has been established that short sleep duration can …

Abstract Background and Aims There are currently no clear conclusions about whether
major depression (MD) and bipolar disorder (BD) increase the risk of erectile dysfunction …

Background Aspirin, as one of the most commonly used drugs, possesses a broad spectrum
of therapeutic applications. Presently, the potential association between aspirin usage and …

Background Sleep quality and duration have been investigated for their association with
health. Insomnia affects up to one-third of adults and may impact male erectile function. In …

Background Multiple risk factors of stroke have been identified in previous studies; however,
the causal role of snoring in the onset of stroke is less investigated. To clarify the causal …

Background: The interaction between intestinal microbiota and infertility is less researched.
This study was performed to investigate the causal association between gut microbiota and …

Background Depression and the increased risk of sarcopenia are prevalent among the
elderly population. However, the causal associations between these factors remain unclear …

Objective Observational studies have reported that mental disorders are comorbid with
temporomandibular joint disorder (TMD). However, the causal relationship remains …

Chronic kidney disease (CKD) is prevalent globally with limited therapeutic drugs available.
To systemically identify novel proteins involved in the pathogenesis of CKD and possible …