Current treatment landscape for early triple-negative breast cancer (TNBC)
J Lee - Journal of clinical medicine, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) accounts for 15–20% of all breast cancers and is
characterized by an aggressive nature and a high rate of recurrence despite neoadjuvant …
characterized by an aggressive nature and a high rate of recurrence despite neoadjuvant …
Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome
To elucidate the effects of neoadjuvant chemotherapy (NAC), we conduct whole
transcriptome profiling coupled with histopathology analyses of a longitudinal breast cancer …
transcriptome profiling coupled with histopathology analyses of a longitudinal breast cancer …
The impact of lag time to cancer diagnosis and treatment on clinical outcomes prior to the COVID-19 pandemic: A scoping review of systematic reviews and meta …
Background: The COVID-19 pandemic has disrupted cancer care, raising concerns
regarding the impact of wait time, or 'lag time', on clinical outcomes. We aimed to …
regarding the impact of wait time, or 'lag time', on clinical outcomes. We aimed to …
Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel
CM Scribano, J Wan, K Esbona, JB Tucker… - Science translational …, 2021 - science.org
Paclitaxel (Taxol) is a cornerstone of cancer treatment. However, its mechanism of
cytotoxicity is incompletely understood and not all patients benefit from treatment. We show …
cytotoxicity is incompletely understood and not all patients benefit from treatment. We show …
Quality of life and illness perceptions in patients with breast cancer using a fasting mimicking diet as an adjunct to neoadjuvant chemotherapy in the phase 2 DIRECT …
RT Lugtenberg, S de Groot, AA Kaptein… - Breast cancer research …, 2021 - Springer
Purpose In the phase II DIRECT study a fasting mimicking diet (FMD) improved the clinical
response to neoadjuvant chemotherapy as compared to a regular diet. Quality of Life (QoL) …
response to neoadjuvant chemotherapy as compared to a regular diet. Quality of Life (QoL) …
[HTML][HTML] Resistance of breast cancer cells to paclitaxel is associated with low expressions of miRNA-186 and miRNA-7
V Apollonova, D Plevako, A Garanin… - Cancer Drug …, 2023 - ncbi.nlm.nih.gov
Aim: Neo-adjuvant chemotherapy is a common approach for the complex treatment of breast
cancer (BC) and paclitaxel (PTX) is frequently included in the therapeutic regimen. However …
cancer (BC) and paclitaxel (PTX) is frequently included in the therapeutic regimen. However …
Comparative efficacy and safety of PD-1/PD-L1 inhibitors in triple negative breast cancer: a systematic review and network meta-analysis of randomized controlled …
I Elmakaty, R Abdo, A Elsabagh, A Elsayed… - Cancer Cell …, 2023 - Springer
Abstract Background Triple-Negative Breast Cancer (TNBC) is a lethal subtype of breast
cancer with limited treatment options. The purpose of this Network Meta-Analysis (NMA) is to …
cancer with limited treatment options. The purpose of this Network Meta-Analysis (NMA) is to …
Drug-resistant profiles of extracellular vesicles predict therapeutic response in TNBC patients receiving neoadjuvant chemotherapy
Background Predicting tumor responses to neoadjuvant chemotherapy (NAC) is critical for
evaluating prognosis and designing treatment strategies for patients with breast cancer; …
evaluating prognosis and designing treatment strategies for patients with breast cancer; …
A Canadian national guideline on the neoadjuvant treatment of invasive breast cancer, including patient assessment, systemic therapy, and local management …
S Gandhi, M Brackstone, NJL Hong, D Grenier… - Breast cancer research …, 2022 - Springer
Purpose The neoadjuvant treatment of breast cancer (NABC) is a rapidly changing area that
benefits from guidelines integrating evidence with expert consensus to help direct practice …
benefits from guidelines integrating evidence with expert consensus to help direct practice …
Evaluate the clinical outcome of nanoparticle albumin-bound paclitaxel on breast cancer treatment: a systematic review and meta-analysis
Y Shariati, FS Kahrizsangi… - … Research in Dental …, 2022 - ebooks.manu2sent.com
Background and aim: Nanoparticle albumin-bound paclitaxel can have a higher response
rate than paclitaxel in women with metastatic breast cancer. Therefore, the present study …
rate than paclitaxel in women with metastatic breast cancer. Therefore, the present study …